SCHEMBL3568418

SCHEMBL3568418

Cc1ccccn1.[Pt]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9007545 1.00 GRM5 (0.48)
SCHEMBL2684 0.97
SCHEMBL29472848 0.97
SCHEMBL29599136 0.97 KDM4E (0.50)
SCHEMBL4733426 0.97 KDM4E (0.50)
SCHEMBL16322907 0.97 KDM4E (0.50)
SCHEMBL25382981 0.94
SCHEMBL21274595 0.94
SCHEMBL19540310 0.94 GRM5 (0.48)
Hydrochloric Acid SCHEMBL21723652 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108289922-A Therapeutic methods and compositions for treating non-small cell lung cancer 友杏生技医药股份有限公司 2018-07-17 CN claimed
CN-101775040-B Process for preparing picoplatin NANJING CUCCESS PHARMACEUTICAL CO LTD 2012-05-09 CN claimed
CN-101775040-A New method for preparing picoplatin NANJING CUCCESS PHARMACEUTICAL 2010-07-14 CN claimed
CN-101056620-A Method of treating cancer by intraperitoneal administration of lipid-based platinum compound preparation TRANSAVE INC (US) 2007-10-17 CN claimed
CN-112955178-B Combination of LIF inhibitor and platinum-based antitumor agent for the treatment of cancer 免疫医疗有限公司 2025-03-11 CN disclosed
CN-118267470-A Anti-SIRP alpha antibodies 赛罗帕私人有限公司 2024-07-02 CN disclosed
CN-117924486-A Anti-CD 27 antibodies 默沙东有限责任公司 2024-04-26 CN disclosed
CN-110650976-B Anti-SIRP alpha antibodies 赛罗帕私人有限公司 2024-04-19 CN disclosed
CN-115003303-B PRMT5 inhibitors 默沙东公司 2024-03-08 CN disclosed
CN-115087638-B PRMT5 inhibitors 默沙东公司 2023-11-24 CN disclosed
CN-109890846-B anti-CD 27 antibodies 默沙东有限责任公司 2023-10-24 CN disclosed
CN-110996958-B Stable lyophilisates comprising 5, 10-methylene- (6R) -tetrahydrofolate and dicarboxylic acids 默克专利股份有限公司 2023-05-12 CN disclosed
US-20050026896-A1 Platinum(II) and platinum(IV) complexes and their use FAUSTUS FORSCHUNGS CIE. TRANSLATIONAL CANCER RESEARCH GMBH 2005-02-03 US disclosed
WO-2004109290-A2 METHODS FOR IDENTIFYING MODULATORS OF KINESIN ACTIVITY ROSETTA INPHARMATICS LLC (US) 2004-12-16 WO disclosed
EP-1419166-A2 PLATINUM(II)- AND PLATINUM(IV)-COMPLEXES AND THEIR USE Faustus Forschungs Cie. Translational Cancer Research GmbH (DE) 2004-05-19 EP disclosed
WO-2003106417-A1 MITOTIC KINESIN INHIBITORS MERCK & CO., INC. (US) 2003-12-24 WO disclosed
CN-1430515-A Combination therapy with vascular damaging activity ANGLOGENE PHARMACEUTICALS LTD (GB) 2003-07-16 CN disclosed
CN-1409708-A Tyrosine kinase inhibitors MERCK & CO INC (US) 2003-04-09 CN disclosed
WO-2003018593-A2 PLATINUM(II)- AND PLATINUM(IV)-COMPLEXES AND THEIR USE FAUSTUS FORSCHUNGS CIE. TRANSLATIONAL CANCER RESEARCH GMBH (DE) 2003-03-06 WO disclosed
CN-1390215-A Tyrosine kinase inhibitors MERCK & CO INC (US) 2003-01-08 CN disclosed