Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3502515 | 0.84 | PTPN2 (0.48) | PTPN2MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL3820707 | 0.82 | PTPN2 (0.52) | PTPN2MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL3573978 | 0.82 | PTPN2 (0.52) | PTPN2MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL3613052 | 0.80 | PTPN2 (0.55) | PTPN2MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL2080982 | 0.79 | PTPN2 (0.48) | PTPN2MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL3569333 | 0.76 | PTPN2 (0.46) | PTPN2MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL8250276 | 0.76 | HDAC1 (0.60) | PTPN2MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL3565432 | 0.75 | PTPN2 (0.50) | PTPN2MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL2082522 | 0.75 | ESR1 (0.52) | PTPN2MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL191958 | 0.75 | HDAC1 (0.51) | PTPN2MAPTKDM4ETDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834034-B2 | Benzothiophene derivatives | MERCK SHARP & DOHME CORP. (US) | 2010-11-16 | — | — | US | disclosed |