Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 15/20 | 0.61 |
| ▸ | NR1H3 | Q13133 | 15/20 | 0.61 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2080813 | 0.84 | NR1H2 (0.74) | NR1H2NR1H3 | |
| SCHEMBL2080817 | 0.84 | NR1H2 (0.74) | NR1H2NR1H3 | |
| SCHEMBL2080834 | 0.79 | NR1H2 (0.66) | NR1H2NR1H3CETP | |
| SCHEMBL1382656 | 0.77 | NR1H2 (1.00) | NR1H2NR1H3 | |
| SCHEMBL1385634 | 0.77 | NR1H2 (1.00) | NR1H2NR1H3 | |
| SCHEMBL1382658 | 0.77 | NR1H2 (1.00) | NR1H2NR1H3 | |
| SCHEMBL29037291 | 0.71 | NR1H2 (0.67) | NR1H2NR1H3CETPSLC6A2SLC6A4 | |
| SCHEMBL8913954 | 0.69 | NR1H2 (0.56) | NR1H2NR1H3CETPSLC6A2SLC6A4 | |
| SCHEMBL20261940 | 0.68 | NR1H2 (0.63) | NR1H2NR1H3SLC6A2SLC6A4 | |
| SCHEMBL10717527 | 0.68 | AOC3 (0.53) | NR1H2NR1H3CETPSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004297-A1 | NOVEL HEXAFLUOROISOPROPANOL DERIVATIVES | DEHMLOW HENRIETTA | 2010-01-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004297-A1 | NOVEL HEXAFLUOROISOPROPANOL DERIVATIVES | NR1H3, NR1H2, NR1I2 | NR1H2 2/4885NR1H3 1/4885CETP 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.