Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RHOC | P08134 | 1/20 | 0.51 |
| ▸ | RHOA | P61586 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30301291 | 0.85 | CA1 (0.60) | CNR1MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL5175715 | 0.84 | KMT2A (0.50) | MEN1CYP1A2CYP2C19KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL9458378 | 0.84 | CA1 (0.59) | CNR1MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3959831 | 0.84 | MEN1 (0.63) | CNR1MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3244925 | 0.83 | CA1 (0.62) | CNR1MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL25381118 | 0.82 | CA1 (0.58) | MEN1KMT2ACA1CA2KDM4E | |
| SCHEMBL12521058 | 0.80 | CHRM2 (0.57) | CNR1MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL12829576 | 0.80 | CA1 (0.57) | MEN1KMT2ACHRM2CA1CA2 | |
| SCHEMBL5184746 | 0.76 | CA1 (0.70) | MEN1KMT2ACA1CA2RAB9A | |
| SCHEMBL11094422 | 0.76 | CHRM2 (0.75) | MEN1CYP2C19KMT2ASMN1; SMN2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |