Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580093 | 1.00 | BACE1 (0.82) | BACE1CTSD | |
| SCHEMBL3580097 | 1.00 | BACE1 (0.82) | BACE1CTSD | |
| SCHEMBL3569918 | 1.00 | BACE1 (0.82) | BACE1CTSD | |
| SCHEMBL3580098 | 1.00 | BACE1 (0.82) | BACE1CTSD | |
| SCHEMBL3580100 | 0.94 | BACE1 (0.72) | BACE1CTSD | |
| SCHEMBL3564479 | 0.94 | BACE1 (0.83) | BACE1CTSD | |
| SCHEMBL3565958 | 0.94 | BACE1 (0.83) | BACE1CTSD | |
| SCHEMBL2176098 | 0.94 | BACE1 (0.83) | BACE1CTSD | |
| SCHEMBL2176103 | 0.94 | BACE1 (0.83) | BACE1CTSD | |
| SCHEMBL3586879 | 0.94 | BACE1 (0.83) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745484-B2 | Beta-secretase modulators and methods of use | AMGEN INC. (US) | 2010-06-29 | — | — | US | claimed |
| US-7745484-B2 | Beta-secretase modulators and methods of use | AMGEN INC. (US) | 2010-06-29 | — | — | US | disclosed |