Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4982874 | 0.98 | KDM4E (0.47) | KDM4ETYRO3DYRK1BALDH1A1HPGD | |
| SCHEMBL9239547 | 0.98 | KDM4E (0.47) | KDM4ETYRO3DYRK1BALDH1A1HPGD | |
| SCHEMBL30586390 | 0.79 | KDM4E (0.37) | KDM4ETYRO3DYRK1BALDH1A1HPGD | |
| SCHEMBL4480587 | 0.79 | KDM4E (0.33) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL4323514 | 0.78 | KDM4E (0.35) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL2009845 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL1590661 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL11486221 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL99268 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL22430792 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1HPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112245440-A | Use of tocotrienol derivatives | 北京蔚蓝之源医药科技有限公司 | 2021-01-22 | — | — | CN | claimed |
| CN-108484605-A | A kind of chloro- 9- of 2- amino -6-（4- acetoxy-3s-acetyl-o-methyl butyl）The preparation method of purine | 上药康丽（常州）药业有限公司 | 2018-09-04 | — | — | CN | claimed |
| EP-2663309-B1 | PROCESSES FOR PREPARING ISOQUINOLINONES AND SOLID FORMS OF ISOQUINOLINONES | INFINITY PHARMACEUTICALS INC (US) | 2017-03-15 | — | — | EP | claimed |
| CN-103648499-B | Processes for preparing isoquinolinones and solid forms of isoquinolinones | 无限药品股份有限公司 | 2017-02-15 | — | — | CN | claimed |
| US-9290497-B2 | Processes for preparing isoquinolinones and solid forms of isoquinolinones | INFINITY PHARMACEUTICALS, INC. (US) | 2016-03-22 | — | — | US | claimed |
| CN-104031048-B | A kind of β-chloroethylnitrosoureas compound and preparation method and use thereof | BEIJING UNIVERSITY OF TECHNOLOGY (CN) | 2016-03-09 | — | — | CN | claimed |
| CN-105294761-A | Impurities of tenofovir disoproxil fumarate or tenofovir, and preparation method thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL TECHNOLOGY CO LTD | 2016-02-03 | — | — | CN | claimed |
| CN-105153163-A | 2,9-disubstituted purine-6-amino hydroxamic acid HDAC (histone deacetylase) inhibitor, preparation method and application | UNIV SHANDONG | 2015-12-16 | — | — | CN | claimed |
| CN-103304601-B | Tenofovir disoproxil new synthetic process | Chengdu Fluorine Bio-tech Co., Ltd. (CN) | 2015-09-30 | — | — | CN | claimed |
| US-20140371450-A1 | PROCESSES FOR PREPARING ISOQUINOLINONES AND SOLID FORMS OF ISOQUINOLINONES | HCR COLLATERAL MANAGEMENT, LLC | 2014-12-18 | — | — | US | claimed |
| WO-2005023811-A1 | PROCESS FOR THE PREPARATION OF (1S, 4R) -CIS-4-‘2-AMINO-6CHLORO-9H-PURIN-9-YL!-2-CYCLOPENTENE-1-METHANOL | GLAXO GROUP LIMITED (GB) | 2005-03-17 | — | — | WO | claimed |
| WO-2004096286-A2 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | claimed |
| WO-2004096235-A2 | ANTI-CANCER PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | claimed |
| EP-0861841-B1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS COMPANY (JP) | 2001-04-04 | — | — | EP | claimed |
| US-5994541-A | Process for producing 2-amino-6-iodopurine | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-11-30 | — | — | US | claimed |
| CN-1226602-A | Fast culture media for mycobaterium tuberculosis and preparation thereof | LIU ZHAOYUN (CN) | 1999-08-25 | — | — | CN | claimed |
| EP-0861841-A1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1998-09-02 | — | — | EP | claimed |
| US-5264561-A | Reaction with an acid anhydride in the presence of a catalyst such as zirconium oxide, titanium oxide, alumina and acetic anhydride | JAPAN TOBACCO INC. (JP) | 1993-11-23 | — | — | US | claimed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| US-3939089-A | PEROXYSULFATE | TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) | 1976-02-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371450-A1 | PROCESSES FOR PREPARING ISOQUINOLINONES AND SOLID FORMS OF ISOQUINOLINONES | PIK3CA, PDPK1, AKT3 | KDM4E 3595/4885TYRO3 1890/4885DYRK1B 1019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.