SCHEMBL357159

SCHEMBL357159

O=C1[N]C=CC=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72400 0.66
SCHEMBL8625540 0.64
SCHEMBL3870589 0.63
SCHEMBL1465460 0.55
SCHEMBL6780303 0.55
SCHEMBL28735200 0.55
SCHEMBL30923519 0.55
Selenium SCHEMBL29864615 0.55
Charcoal, Activated SCHEMBL29797978 0.55
SCHEMBL55947 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1096 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148775-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING OSAKA UNIVERSITY (JP) 2024-05-09 US claimed
EP-4326721-A1 SPIROCYCLIC IMIDAZOLIDINONES AND IMIDAZOLIDINEDIONES FOR TREATMENT OF LIGHT CHAIN AMYLOIDOSIS Protego Biopharma, Inc. (US) 2024-02-28 EP claimed
US-20240051960-A1 SPIROCYCLIC IMIDAZOLIDINONES AND IMIDAZOLIDINEDIONES FOR TREATMENT OF LIGHT CHAIN AMYLOIDOSIS PROTEGO BIOPHARMA, INC. 2024-02-15 US claimed
EP-4299744-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING OSAKA UNIVERSITY (JP) 2024-01-03 EP claimed
US-20230348522-A1 METHOD FOR PRODUCING BICYCLIC PHOSPHORAMIDITE DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-11-02 US claimed
US-20230340008-A1 BRIDGED NUCLEOSIDE AND NUCLEOTIDE USING SAME JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NATIONAL INSTITUTE OF HEALTH SCIENCES (JP) 2023-10-26 US claimed
US-20230322840-A1 BRIDGED NUCLEOSIDE AND NUCLEOTIDE LIID PHARMACEUTICALS, INC. (JP) 2023-10-12 US claimed
WO-2023167094-A1 5'-MODIFIED NUCLEOSIDE AND NUCLEOTIDE USING SAME 国立大学法人大阪大学 2023-09-07 WO claimed
US-20230265120-A1 NUCLEOSIDE DERIVATIVE AND USE THEREOF NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) 2023-08-24 US claimed
US-20230257413-A1 ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF RIKEN GENESIS CO., LTD. (JP) 2023-08-17 US claimed
US-5157037-A α-arylacrylates substituted by a heterocyclic radical, and fungicides which contain these compounds BASF AKTIENGESELLSCHAFT (DE) 1992-10-20 US claimed
EP-0370902-B1 USE OF CHROMANE DERIVATIVES IN THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF DEPRESSIVE CONDITIONS ELF SANOFI (FR) 1992-08-26 EP claimed
EP-0489300-A2 Tetralones with pharmacological activity J. URIACH &amp; CIA. S.A. (ES) 1992-06-10 EP claimed
EP-0450487-A1 Benzoxazine derivatives, method for their preparation and their use for treating or prophylaxis of diseases HOECHST AKTIENGESELLSCHAFT (DE) 1991-10-09 EP claimed
US-5043352-A Chroman derivatives for the treatment of depressive states SANOFI (FR) 1991-08-27 US claimed
US-4931454-A Azachroman derivatives with effects on the cardiovascular system MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-06-05 US claimed
EP-0370902-A2 Use of chromane derivatives in the preparation of a medicament for the treatment of depressive conditions ELF SANOFI (FR) 1990-05-30 EP claimed
EP-0350691-A2 Heterocyclically substituted alpha-aryl-acrylic-acid esters, and fungicides containing these compounds BASF Aktiengesellschaft (DE) 1990-01-17 EP claimed
EP-0340718-A1 Chroman derivatives MERCK PATENT GmbH (DE) 1989-11-08 EP claimed
EP-0273262-A2 Chroman derivatives MERCK PATENT GmbH (DE) 1988-07-06 EP claimed