Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885170 | 1.00 | CYP1A2 (0.57) | CYP1A2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL3887207 | 1.00 | CYP1A2 (0.57) | CYP1A2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL3893051 | 0.99 | CYP1A2 (0.56) | CYP1A2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL27259282 | 0.91 | CYP1A2 (0.56) | CYP1A2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL9587966 | 0.91 | CYP1A2 (0.56) | CYP1A2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL3893049 | 0.88 | MAPT (0.74) | CYP1A2MAPTTP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL10946610 | 0.86 | MAPT (0.46) | CYP1A2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL3886045 | 0.86 | AKR1C3 (0.47) | CYP1A2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL13316457 | 0.86 | TDP1 (0.48) | CYP1A2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL27259406 | 0.86 | TDP1 (0.48) | CYP1A2MAPTTP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728007-B2 | Therapeutic amides | WAYNE STATE UNIVERSITY (US) | 2010-06-01 | — | — | US | disclosed |
| US-7585863-B2 | Antitumor agents; such as (2-(4-(7-Chloro-2-quinoxalinyl)oxy)propionylamino ethansulfonic acid; {2-{4-(7-Chloro-quinoxalin-2-yloxy)-phenoxy}propionyl amino}acetic acid | WAYNE STATE UNIVERSITY (US) | 2009-09-08 | — | — | US | disclosed |
| US-20090076073-A1 | THERAPEUTIC AMIDES | WAYNE STATE UNIVERSITY | 2009-03-19 | — | — | US | disclosed |
| US-20060293333-A1 | Antitumor agents; such as (2-(4-(7-Chloro-2-quinoxalinyl)oxy)propionylamino ethansulfonic acid; {2-{4-(7-Chloro-quinoxalin-2-yloxy)-phenoxy}propionyl amino}acetic acid | WAYNE STATE UNIVERSITY | 2006-12-28 | — | — | US | disclosed |
| US-7109341-B2 | Therapeutic amides | WAYNE STATE UNIVERSITY (US) | 2006-09-19 | — | — | US | disclosed |
| US-20040132618-A1 | Therapeutic amides | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293333-A1 | Antitumor agents; such as (2-(4-(7-Chloro-2-quinoxalinyl)oxy)propionylamino ethansulfonic acid; {2-{4-(7-Chloro-quinoxalin-2-yloxy)-phenoxy}propionyl amino}acetic acid | ANXA5, TP53, PRDX6 | CYP1A2 3160/4885MAPT 4832/4885TP53 2/4885 |
| US-20040132618-A1 | Therapeutic amides | HDAC5, HDAC6, ASAH2 | CYP1A2 3469/4885MAPT 3239/4885TP53 103/4885 |
| US-20090076073-A1 | THERAPEUTIC AMIDES | HDAC5, HDAC6, ASAH2 | CYP1A2 3511/4885MAPT 3590/4885TP53 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.