SCHEMBL3573585

SCHEMBL3573585

O=C(O)N[C@H]1CCOC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1669260 1.00
SCHEMBL19813207 0.88 KDM4E (0.45)
SCHEMBL515191 0.82 KDM4E (0.52)
SCHEMBL1146625 0.82 KDM4E (0.52)
SCHEMBL14177128 0.82
SCHEMBL23169663 0.82
SCHEMBL12409488 0.82 KDM4E (0.52)
SCHEMBL14169375 0.81
SCHEMBL19538682 0.80
SCHEMBL12341600 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121873017-A Preparation method of (S) - (2-oxo-tetrahydrofuran-3-yl) -carbamate 山东省农药科学研究院 2026-04-17 CN disclosed
CN-121873017-A Preparation method of (S) - (2-oxo-tetrahydrofuran-3-yl) -carbamate 山东省农药科学研究院 2026-04-17 CN disclosed
EP-3458584-B1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN CONSEJO SUPERIOR INVESTIGACION (ES) 2021-07-07 EP disclosed
US-10683493-B2 Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2020-06-16 US disclosed
US-20190194638-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN TECHNICAL UNIVERSITY OF DARMSTADT (DE) 2019-06-27 US disclosed
EP-3458584-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN Consejo Superior De Investigaciones Científicas (ES) 2019-03-27 EP disclosed
WO-2017198717-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2017-11-23 WO disclosed
US-7728005-B2 Ether derivative AJINOMOTO CO., INC. (JP) 2010-06-01 US disclosed
US-7329685-B2 1-Phenyl-2-oxo-3-sulfonylamino-pyrrolidine derivatives and related compounds as factor Xa inhibitors for the treatment of acute vascular diseases GLAXO GROUP LIMITED (GB) 2008-02-12 US disclosed
US-20070203206-A1 2-Pyrrolidone Derivatives And Use Thereof As Factor Xa Inhibitors GLAXO GROUP LIMITED (GB) 2007-08-30 US disclosed
US-20060270693-A1 Ether derivative AJINOMOTO CO., INC. (JP) 2006-11-30 US disclosed
EP-1635817-B1 1-PHENYL-2-OXO-3-SULFONYLAMINO-PYRROLIDINE DERIVATIVES AND RELATED COMPOUNDS AS FACTOR XA INHIBITORS FOR THE TREATMENT OF ACUTE VASCULAR DISEASES GLAXO GROUP LTD (GB) 2006-11-22 EP disclosed
EP-1679296-A1 ETHER DERIVATIVE Ajinomoto Co., Inc. (JP) 2006-07-12 EP disclosed
US-20060148879-A1 1-Phenyl-2-oxo-3-sulfonylamino-pyrrolidine derivatives and related compounds as factor xa inhibitors for the treatment of acute vascular diseases GLAXO GROUP LIMITED (GB) 2006-07-06 US disclosed
EP-1635817-A1 1-PHENYL-2-OXO-3-SULFONYLAMINO-PYRROLIDINE DERIVATIVES AND RELATED COMPOUNDS AS FACTOR XA INHIBITORS FOR THE TREATMENT OF ACUTE VASCULAR DISEASES GLAXO GROUP LIMITED (GB) 2006-03-22 EP disclosed
EP-1633347-A1 2-PYRROLIDONE DERIVATIVES AND USE THEREOF AS FACTOR XA INHIBITORS GLAXO GROUP LIMITED (GB) 2006-03-15 EP disclosed
WO-2004110435-A1 1-PHENYL-2-OXO-3-SULFONYLAMINO-PYRROLIDINE DERIVATIVES AND RELATED COMPOUNDS AS FACTOR XA INHIBITORS FOR THE TREATMENT OF ACUTE VASCULAR DISEASES GLAXO GROUP LIMITED (GB) 2004-12-23 WO disclosed
WO-2004110434-A1 2-PYRROLIDONE DERIVATIVES AND USE THEREOF AS FACTOR XA INHIBITORS GLAXO GROUP LIMITED (GB) 2004-12-23 WO disclosed