Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 15/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 2/20 | 0.35 |
| ▸ | UBE2N | P61088 | 2/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599490 | 0.87 | CETP (0.42) | CETPTACR1 | |
| SCHEMBL1600356 | 0.86 | CETP (0.42) | CETPTACR1 | |
| SCHEMBL1599506 | 0.83 | CETP (0.39) | CETPTACR1 | |
| SCHEMBL1600347 | 0.83 | CETP (0.43) | CETPTACR1 | |
| SCHEMBL4220331 | 0.82 | CETP (0.37) | CETPAPAF1UBE2NIDERECQL | |
| SCHEMBL4223082 | 0.81 | CETP (0.38) | CETPAPAF1UBE2NIDERECQL | |
| SCHEMBL1599615 | 0.81 | CETP (0.41) | CETPTACR1 | |
| SCHEMBL1599609 | 0.81 | CETP (0.42) | CETPTACR1SGMS1SGMS2 | |
| SCHEMBL4217794 | 0.81 | CETP (0.37) | CETPAPAF1UBE2NIDERECQL | |
| SCHEMBL1599481 | 0.80 | CETP (0.36) | CETPTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076021-A1 | Organic Compounds | IMASE HIDETOMO | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076021-A1 | Organic Compounds | CETP, NPC1, LCAT | CETP 1/4885TACR1 1439/4885APAF1 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.