SCHEMBL357428

SCHEMBL357428

Clc1ccc(COOCc2ccc(Cl)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.64
AGXT P21549 2/20 0.64
MAOB P27338 5/20 0.50
APP P05067 1/20 0.50
LMNA P02545 1/20 0.47
CYP2A6 P11509 1/20 0.47
TAAR1 Q96RJ0 1/20 0.46
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
SLC6A4 P31645 1/20 0.44
NR4A2 P43354 1/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
SIGMAR1 Q99720 1/20 0.43
MAOA P21397 1/20 0.42
CHRNB2 P17787 1/20 0.42
CHRNA4 P43681 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10296080 0.85 IDO1 (0.54) IDO1AGXTMAOBAPPTAAR1
SCHEMBL4995796 0.82 IDO1 (0.64) IDO1AGXTMAOBAPPLMNA
SCHEMBL9821418 0.80 IDO1 (0.61) IDO1AGXTMAOBAPPLMNA
SCHEMBL8995755 0.80 IDO1 (0.61) IDO1AGXTMAOBAPPLMNA
SCHEMBL1109924 0.79 IDO1 (0.54) IDO1AGXTMAOBAPPLMNA
SCHEMBL1139040 0.78 IDO1 (0.58) IDO1AGXTMAOBAPPLMNA
SCHEMBL1146232 0.78 IDO1 (0.58) IDO1AGXTMAOBAPPLMNA
SCHEMBL2985125 0.78 IDO1 (0.58) IDO1AGXTMAOBAPPLMNA
SCHEMBL8716806 0.78 IDO1 (0.58) IDO1AGXTMAOBAPPLMNA
SCHEMBL31273 0.78 IDO1 (0.58) IDO1AGXTMAOBAPPLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119144205-A Heavy anti-corrosion coating containing polyurethane microcapsule, preparation method and coating thereof 山东省交通规划设计院集团有限公司 2024-12-17 CN claimed
US-20240326361-A1 SEALANT COMPOSITION FOR SELF-SEALING PNEUMATIC TIRE THE GOODYEAR TIRE & RUBBER COMPANY 2024-10-03 US claimed
EP-4438280-A1 SEALANT COMPOSITION FOR SELF-SEALING PNEUMATIC TIRE The Goodyear Tire & Rubber Company (US) 2024-10-02 EP claimed
US-10589478-B2 Pneumatic tire having sealant layer Triangle Tyre Co. Ltd. (CN) 2020-03-17 US claimed
US-20160167321-A1 PNEUMATIC TIRE HAVING SEALANT LAYER TRIANGLE TYRE CO LTD (CN) 2016-06-16 US claimed
US-8460494-B2 Tire with tread and preparation thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2013-06-11 US claimed
EP-1533108-B1 Pneumatic tire with built-in colored sealant layer and method of preparing said pneumatic tire GOODYEAR TIRE & RUBBER (US) 2012-09-26 EP claimed
US-20120012236-A1 TIRE WITH TREAD AND PREPARATION THEREOF GOODYEAR TIRE & RUBBER COMPANY, THE 2012-01-19 US claimed
EP-1457308-B1 Pneumatic tire having built-in sealant layer and preparation thereof GOODYEAR TIRE & RUBBER (US) 2008-10-01 EP claimed
EP-1721932-B1 Pneumatic tire with built-in sealant containing pre-hydrophobated silica GOODYEAR TIRE & RUBBER (US) 2008-08-13 EP claimed
US-20050205184-A1 Pneumatic tire with built-in colored sealant with viscoelastic modulus property THE GOODYEAR TIRE & RUBBER COMPANY 2005-09-22 US claimed
US-20050205186-A1 Pneumatic tire with built-in colored sealant layer which contains carbon black THE GOODYEAR TIRE & RUBBER COMPANY 2005-09-22 US claimed
US-20050113502-A1 Pneumatic tire with built-in colored sealant layer FITZHARRIS WALL JENNIFER E (US) 2005-05-26 US claimed
EP-1533108-A2 Pneumatic tire with built-in colored sealant layer THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-05-25 EP claimed
US-6837287-B2 Self-sealing pneumatic tire and preparation thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-01-04 US claimed
EP-1457308-A1 Pneumatic tire having built-in sealant layer and preparation thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2004-09-15 EP claimed
US-20040159386-A1 Pneumatic tire having built-in sealant layer and preparation thereof GOODYEAR TIRE & RUBBER COMPANY,THE 2004-08-19 US claimed
US-20030230376-A1 Self-sealing pneumatic tire and preparation thereof GOODYEAR TIRE & RUBBER COMPANY, THE 2003-12-18 US claimed
US-4895610-A LAYER OF BUTYL RUBBER, POLYISOBUTYLENE, OIL EXTENDER, PEROXIDE, SULFUR THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-01-23 US claimed
EP-0135463-A1 Self-sealing pneumatic tire and method of manufacturing same THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-03-27 EP claimed