⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL15769458 | 0.67 | HSP90AA1 (0.92) | — | |
| SCHEMBL226937 | 0.64 | — | — | |
| SCHEMBL857009 | 0.64 | — | — | |
| Water SCHEMBL4239659 | 0.64 | HSP90AA1 (0.93) | — | |
| SCHEMBL908120 | 0.63 | — | — | |
| SCHEMBL27136 | 0.62 | — | — | |
| SCHEMBL8920730 | 0.61 | — | — | |
| SCHEMBL7992613 | 0.61 | — | — | |
| SCHEMBL2373403 | 0.60 | HDAC8 (0.33) | — | |
| SCHEMBL4458 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 801 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | claimed |
| US-11753408-B2 | Compounds and method for blocking transmission of malarial parasite | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-09-12 | — | — | US | claimed |
| US-20230265103-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME THERAPEUTICS LLC | 2023-08-24 | — | — | US | claimed |
| US-20230183233-A1 | Bicyclic Pyridin-2-one and pyrimidin-4-one Derivatives Useful As a Factor XIa Inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-15 | — | — | US | claimed |
| US-20230097157-A1 | Bicyclic Pyridin-2-one and pyrimidin-4-one Derivatives Useful As a Factor XIa Inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-30 | — | — | US | claimed |
| US-20220017505-A1 | AMINOQUINAZOLINONE AND AMINOISOQUINOLINONE DERIVATIVES AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2022-01-20 | — | — | US | claimed |
| US-20210246137-A1 | COMPOUNDS AND METHOD FOR BLOCKING TRANSMISSION OF MALARIAL PARASITE | THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-08-12 | — | — | US | claimed |
| US-10787444-B2 | Compounds for the modulation of myc activity | SYROS PHARMACEUTICALS, INC. (US) | 2020-09-29 | — | — | US | claimed |
| EP-3019490-B1 | N,6-BIS(ARYL OR HETEROARYL)-1,3,5-TRIAZINE-2,4-DIAMINE COMPOUNDS AS IDH2 MUTANTS INHIBITORS FOR THE TREATMENT OF CANCER | AGIOS PHARMACEUTICALS INC (US) | 2020-06-03 | — | — | EP | claimed |
| CN-110680813-A | Use of naphthoquinone derivatives as IDO1 and/or TDO inhibitors | 北京大学 | 2020-01-14 | — | — | CN | claimed |
| EP-0272827-A2 | 3-Heterocyclicthiomethyl cephalosphorins | ZENECA Pharma S.A. (FR) | 1988-06-29 | — | — | EP | claimed |
| EP-0269298-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions | ICI PHARMA (FR) | 1988-06-01 | — | — | EP | claimed |
| EP-0267733-A2 | Cephalosporin compounds, process for their preparation and pharmaceutical compositions containing them | ZENECA Pharma S.A. (FR) | 1988-05-18 | — | — | EP | claimed |
| US-4678781-A | BACTERICIDAL ANTIBIOTICS | ICI PHARMA (FR) | 1987-07-07 | — | — | US | claimed |
| EP-0225182-A2 | Cephalosporin compounds | ICI PHARMA (FR) | 1987-06-10 | — | — | EP | claimed |
| EP-0187456-A1 | Cephalosporin derivatives | ICI PHARMA (FR) | 1986-07-16 | — | — | EP | claimed |
| EP-0182633-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1986-05-28 | — | — | EP | claimed |
| EP-0164944-A1 | Cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-12-18 | — | — | EP | claimed |
| US-4501739-A | BACTERICIDES, ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1985-02-26 | — | — | US | claimed |
| EP-0127992-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1984-12-12 | — | — | EP | claimed |