Levulinic Acid

Levulinic Acid

SCHEMBL357673

CC(=O)CCC(=O)[O-].CCCC[n+]1ccn(C)c1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
HSP90AA1 P07900 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CA1 P00915 1/20 0.36
PABPC1 P11940 1/20 0.33
FDPS P14324 5/20 0.32
FFAR3 O14843 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
FABP3 P05413 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL18575091 0.94 CA1 (0.40) MEN1HSP90AA1KMT2ASMN1; SMN2CA1
Butyric Acid SCHEMBL507692 0.90 FFAR3 (0.42) MEN1HSP90AA1KMT2ASMN1; SMN2CA1
Valeric Acid SCHEMBL446966 0.90 CA1 (0.47) MEN1HSP90AA1KMT2ASMN1; SMN2CA1
Hexanoate SCHEMBL19406559 0.89 FABP3 (0.42) MEN1HSP90AA1KMT2ASMN1; SMN2CA1
Acetic Acid SCHEMBL35015 0.88 MEN1 (0.43) MEN1HSP90AA1KMT2ASMN1; SMN2PABPC1
Octanoic Acid SCHEMBL3125477 0.87 FABP3 (0.44) MEN1HSP90AA1KMT2ASMN1; SMN2CA1
Propionic Acid SCHEMBL358643 0.87 MEN1 (0.39) MEN1HSP90AA1KMT2ASMN1; SMN2PABPC1
Bicarbonate SCHEMBL5032083 0.87 MEN1 (0.41) MEN1HSP90AA1KMT2ASMN1; SMN2PABPC1
Glycolic Acid SCHEMBL18575074 0.85 MEN1 (0.38) MEN1HSP90AA1KMT2ASMN1; SMN2CA1
Levulinic Acid SCHEMBL356603 0.85 MEN1 (0.35) MEN1HSP90AA1KMT2ASMN1; SMN2FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2414476-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. du Pont de Nemours and Company (US) 2012-02-08 EP claimed
US-20120011886-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY 2012-01-19 US claimed
WO-2010117836-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-14 WO claimed
US-20100143992-A1 Process for Fermentive Preparation of Alcohols and Recovery of Product E. I DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 US claimed
US-20100144000-A1 PROCESS FOR FERMENTIVE PREPARATION FO ALCOHOLS AND RECOVERY OF PRODUCT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 US claimed
WO-2010065606-A2 PROCESS FOR FERMENTIVE PREPARATION OF ALCOHOLS AND RECOVERY OF PRODUCT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 WO claimed
US-20100140166-A1 PROCESS FOR FERMENTIVE PREPARATION OF ALCOHOLS AND RECOVERY OF PRODUCT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 US claimed
US-20100143995-A1 Process for Fermentive Preparation of Alcohols and Recovery of Product E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 US claimed
EP-2414476-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. du Pont de Nemours and Company (US) 2012-02-08 EP disclosed
US-20120011886-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY 2012-01-19 US disclosed
WO-2010117836-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-14 WO disclosed
US-20100143992-A1 Process for Fermentive Preparation of Alcohols and Recovery of Product E. I DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 US disclosed
US-20100144000-A1 PROCESS FOR FERMENTIVE PREPARATION FO ALCOHOLS AND RECOVERY OF PRODUCT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 US disclosed
US-20100143993-A1 PROCESS FOR FERMENTIVE PREPARATIONFOR ALCOLHOLS AND RECOVERY OF PRODUCT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 US disclosed
US-20100143999-A1 PROCESS FOR FERMENTIVE PREPARATION OF ALCOHOLS AND RECOVERY OF PRODUCT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 US disclosed
WO-2010065606-A2 PROCESS FOR FERMENTIVE PREPARATION OF ALCOHOLS AND RECOVERY OF PRODUCT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 WO disclosed
US-20100140166-A1 PROCESS FOR FERMENTIVE PREPARATION OF ALCOHOLS AND RECOVERY OF PRODUCT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 US disclosed
US-20100143994-A1 PROCESS FOR FERMENTIVE PREPARATION OF ALCOHOLS AND RECOVERY OF PRODUCT E. I. DU PONT DE MEMOURS AND COMPANY 2010-06-10 US disclosed
US-20100139154-A1 PROCESS FOR FERMENTIVE PREPARATION OF ALCOHOLS AND RECOVERY OF PRODUCT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 US disclosed
US-20100143995-A1 Process for Fermentive Preparation of Alcohols and Recovery of Product E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 US disclosed