SCHEMBL3577446

SCHEMBL3577446

NC(CCOCc1ccccc1)C1CCNCC1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.43
SLC6A4 P31645 4/20 0.43
SLC6A3 Q01959 4/20 0.43
HTR1A P08908 3/20 0.43
GBA1 P04062 3/20 0.41
TACR1 P25103 3/20 0.40
REN P00797 2/20 0.39
TSHR P16473 1/20 0.39
HRH1 P35367 1/20 0.38
UGCG Q16739 2/20 0.38
GBA2 Q9HCG7 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3580578 0.85 TACR1 (0.46) SLC6A2SLC6A4SLC6A3HTR1AGBA1
SCHEMBL8969997 0.80 GBA1 (0.47) SLC6A2SLC6A4SLC6A3GBA1HRH1
SCHEMBL3578666 0.79 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3HRH1
SCHEMBL27526570 0.78 GBA1 (0.45) SLC6A2SLC6A4SLC6A3GBA1
SCHEMBL27478385 0.77 DPP4 (0.51) SLC6A2SLC6A4SLC6A3GBA1HRH1
SCHEMBL2185547 0.74 GBA1 (0.56) SLC6A2SLC6A4SLC6A3HTR1AGBA1
SCHEMBL25308033 0.73 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3HTR1AGBA1
Hydrochloric Acid SCHEMBL26637622 0.73 GBA1 (0.54) SLC6A2SLC6A4SLC6A3HTR1AGBA1
SCHEMBL7029186 0.72 GBA1 (0.40) SLC6A2SLC6A4SLC6A3HTR1AGBA1
SCHEMBL7982457 0.72 SLC6A2 (0.51) SLC6A2SLC6A4SLC6A3HTR1AGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed
EP-1885693-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 Wurster, Siegfried (FI) 2008-02-13 EP disclosed
WO-2006123020-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 JUVANTIA PHARMA LTD OY (FI) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 SLC6A2 735/4885SLC6A4 151/4885SLC6A3 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.