SCHEMBL3578552

SCHEMBL3578552

O=C1CCC(Br)C(=O)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19370773 1.00
SCHEMBL25036502 0.76
SCHEMBL9256 0.74
Ammonia Solution, Strong SCHEMBL23360905 0.72
SCHEMBL528253 0.70
SCHEMBL8030518 0.70
SCHEMBL493044 0.70
SCHEMBL5031751 0.70
SCHEMBL22166575 0.70
SCHEMBL16556682 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 896 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240368083-A1 SUBSTITUTED 3-((3-AMINOPHENYL)AMINO)PIPERIDINE-2,6-DIONE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH CELGENE CORP (US) 2024-11-07 US claimed
EP-4398904-A1 SELECTED COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 Therapeutics, Inc. (US) 2024-07-17 EP claimed
CN-117720516-A Advantageous crystalline forms of selective BRD9 degrading agents C4医药公司 2024-03-19 CN claimed
CN-116462627-A Preparation method of 3-bromopiperidine-2, 6-dione 南京优氟医药科技有限公司 2023-07-21 CN claimed
WO-2023039208-A1 SELECTED COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2023-03-16 WO claimed
EP-1252144-B1 SUBSTITUTED GLUTARIMIDES AND USE THEREOF IL-12 PRODUCTION INHIBITORS GRUENENTHAL GMBH (DE) 2009-12-09 EP claimed
EP-1456197-B1 PIPERIDINE-2,6-DIONES THAT ARE HETEROCYCLICALLY SUBSTITUTED IN POSITION 3 GRUENENTHAL GMBH (DE) 2007-02-28 EP claimed
US-7183274-B2 Piperidine-2,6-diones heterocyclically substituted in the 3-position GRUENENTHAL GMBH (DE) 2007-02-27 US claimed
US-20050020581-A1 Piperidine-2,6-diones heterocyclically substituted in the 3-position GRUENENTHAL GMBH (DE) 2005-01-27 US claimed
US-20040048859-A1 Substituted glutarimides and their use as inhibitors of IL-12 production GRUENENTHAL GMBH (DE) 2004-03-11 US claimed
US-20030064987-A1 Substituted glutarimides and their use as inhibitors of IL-12 production GRUENENTHAL GMBH 2003-04-03 US claimed
US-20260146044-A1 AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF INCRELAND (CN) 2026-05-28 US disclosed
US-20260146050-A1 KRAS DEGRADING COMPOUNDS COMPRISING SPIROCYCLIC ANNULATED 2 AMINO-3-CYANO THIOPHENES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2026-05-28 US disclosed
EP-4745142-A1 AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF Increland (CN) 2026-05-20 EP disclosed
EP-4743079-A2 APOL1 INHIBITORS AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2026-05-20 EP disclosed
US-6656937-B2 Immunology moderators; interleukin antagonist; anticancer agents GRUENENTHAL, GMBH (DE) 2003-12-02 US disclosed
WO-2003037853-A1 SUBSTITUTED THIOACETAMIDES CEPHALON, INC. (US) 2003-05-08 WO disclosed
US-20030064987-A1 Substituted glutarimides and their use as inhibitors of IL-12 production GRUENENTHAL GMBH 2003-04-03 US disclosed
EP-1252144-A1 SUBSTITUTED GLUTARIMIDES AND USE THEREOF IL-12 PRODUCTION INHIBITORS Grünenthal GmbH (DE) 2002-10-30 EP disclosed
WO-2001053261-A1 SUBSTITUTED GLUTARIMIDES AND USE THEREOF IL-12 PRODUCTION INHIBITORS Grünenthal GmbH (DE) 2001-07-26 WO disclosed