Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3567777 | 0.90 | GSK3B (0.46) | GSK3BCYP2D6 | |
| SCHEMBL3565173 | 0.89 | GSK3B (0.47) | GSK3BCYP2D6 | |
| SCHEMBL3567458 | 0.84 | GSK3B (0.43) | GSK3BCYP2D6 | |
| SCHEMBL3577559 | 0.83 | GSK3B (0.35) | GSK3BCYP2D6 | |
| SCHEMBL3576890 | 0.82 | GSK3B (0.43) | GSK3BCYP2D6 | |
| SCHEMBL3576893 | 0.82 | GSK3B (0.43) | GSK3BCYP2D6 | |
| SCHEMBL3564721 | 0.80 | GSK3B (0.40) | GSK3BCYP2D6 | |
| SCHEMBL3575296 | 0.80 | GSK3B (0.44) | GSK3BCYP2D6 | |
| SCHEMBL3575298 | 0.80 | GSK3B (0.44) | GSK3BCYP2D6 | |
| SCHEMBL3569153 | 0.79 | GSK3B (0.41) | GSK3BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781440-B2 | Use of substituted 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one and 7-pyrimidinyl-2,3-dihydroimidazo[1,2-a] pyrimidin-5(1H)one derivatives | SANOFI-AVENTIS (FR) | 2010-08-24 | — | — | US | claimed |