Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 20/20 | 0.65 |
| ▸ | CPT1B | Q92523 | 20/20 | 0.65 |
| ▸ | CPT2 | P23786 | 19/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571759 | 0.92 | CPT2 (0.76) | CPT1ACPT1BCPT2 | |
| SCHEMBL3566156 | 0.91 | CPT1A (0.78) | CPT1ACPT1BCPT2 | |
| SCHEMBL30016029 | 0.91 | CPT1A (0.78) | CPT1ACPT1BCPT2 | |
| SCHEMBL3572460 | 0.89 | CPT1A (0.63) | CPT1ACPT1BCPT2 | |
| SCHEMBL3568458 | 0.88 | CPT1A (0.84) | CPT1ACPT1BCPT2 | |
| SCHEMBL3579481 | 0.87 | CPT1A (0.83) | CPT1ACPT1BCPT2 | |
| SCHEMBL3566030 | 0.86 | CPT1A (0.60) | CPT1ACPT1BCPT2 | |
| SCHEMBL3572320 | 0.85 | CPT1A (0.54) | CPT1ACPT1BCPT2 | |
| SCHEMBL752700 | 0.85 | CPT1A (0.84) | CPT1ACPT1BCPT2 | |
| SCHEMBL3568792 | 0.85 | CPT1A (0.59) | CPT1ACPT1BCPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926711-B1 | NOVEL HETEROBICYCLIC DERIVATIVES USEFUL AS INHIBITORS OF LIVER CARNITINE PALMITOYL TRANSFERASE | HOFFMANN LA ROCHE (CH) | 2012-11-07 | — | — | EP | disclosed |
| US-7713996-B2 | Indolyl derivatives which are L-CPT1 inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2010-05-11 | — | — | US | disclosed |
| EP-1926711-A1 | NOVEL HETEROBICYCLIC DERIVATIVES USEFUL AS INHIBITORS OF LIVER CARNITINE PALMITOYL TRANSFERASE | F.HOFFMANN-LA ROCHE AG (CH) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007031429-A1 | NOVEL HETEROBICYCLIC DERIVATIVES USEFUL AS INHIBITORS OF LIVER CARNITINE PALMITOYL TRANSFERASE | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-22 | — | — | WO | disclosed |