Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3585190 | 0.88 | SMN1; SMN2 (0.52) | KMT2AMEN1MAPK1SMN1; SMN2ADRB2 | |
| SCHEMBL3573082 | 0.86 | MAOB (0.51) | KMT2AMEN1KDM4ESMN1; SMN2RECQL | |
| SCHEMBL3575803 | 0.84 | MEN1 (0.43) | KMT2AMEN1KDM4EMAPK1HPGD | |
| SCHEMBL3577627 | 0.84 | MEN1 (0.43) | KMT2AMEN1KDM4EMAPK1HPGD | |
| SCHEMBL3570887 | 0.84 | KMT2A (0.47) | KMT2AMEN1KDM4EHPGDCTSB | |
| SCHEMBL16758733 | 0.83 | FOLH1 (0.51) | SMN1; SMN2CNR1HTT | |
| SCHEMBL3566335 | 0.82 | SMN1; SMN2 (0.51) | KMT2AMEN1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL3574069 | 0.80 | SMN1; SMN2 (0.53) | KDM4EMAPK1HPGDSMN1; SMN2ADRB2 | |
| SCHEMBL3576745 | 0.79 | MEN1 (0.48) | KMT2AMEN1KDM4EMAPK1CTSL | |
| SCHEMBL2228752 | 0.76 | FOLH1 (0.48) | MAPK1SMN1; SMN2CNR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728005-B2 | Ether derivative | AJINOMOTO CO., INC. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20060270693-A1 | Ether derivative | AJINOMOTO CO., INC. (JP) | 2006-11-30 | — | — | US | disclosed |
| EP-1679296-A1 | ETHER DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270693-A1 | Ether derivative | UROD, IL5, IL17A | KMT2A 648/4885MEN1 4235/4885KDM4E 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.