⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13494283 | 1.00 | — | — | |
| SCHEMBL20990282 | 1.00 | — | — | |
| SCHEMBL11358908 | 1.00 | — | — | |
| SCHEMBL15369613 | 1.00 | — | — | |
| SCHEMBL16022511 | 1.00 | — | — | |
| SCHEMBL15369664 | 1.00 | — | — | |
| SCHEMBL15369625 | 1.00 | — | — | |
| SCHEMBL22469160 | 0.83 | FUCA1 (0.35) | — | |
| SCHEMBL22469849 | 0.83 | FUCA1 (0.35) | — | |
| SCHEMBL23029570 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659178-A4 | CHIRAL QUINOLONE INTERMEDIATES. | ABBOTT LAB (US) | 1996-03-27 | — | — | EP | claimed |
| EP-0659178-A1 | CHIRAL QUINOLONE INTERMEDIATES | ABBOTT LABORATORIES (US) | 1995-06-28 | — | — | EP | claimed |
| WO-1994006766-A1 | CHIRAL QUINOLONE INTERMEDIATES | ABBOTT LABORATORIES (US) | 1994-03-31 | — | — | WO | claimed |
| US-5252747-A | Chiral quinolone intermediates | ABBOTT LABORATORIES (US) | 1993-10-12 | — | — | US | claimed |
| US-20170050942-A1 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORP (US) | 2017-02-23 | — | — | US | disclosed |
| US-20150231114-A1 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | PFIZER (US) | 2015-08-20 | — | — | US | disclosed |
| CN-102344398-B | 3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors | INCYTE CORP | 2015-02-25 | — | — | CN | disclosed |
| US-20140155377-A1 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORPORATION (US) | 2014-06-05 | — | — | US | disclosed |
| US-8697870-B2 | 3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2014-04-15 | — | — | US | disclosed |
| CN-103391931-A | A method of treating liver fibrosis | PFIZER LTD | 2013-11-13 | — | — | CN | disclosed |
| EP-1696919-B1 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORP (US) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012114223-A1 | A METHOD OF TREATING LIVER FIBROSIS | PFIZER LIMITED (GB) | 2012-08-30 | — | — | WO | disclosed |
| US-5723627-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-03 | — | — | US | disclosed |
| US-5648493-A | MULTISTAGE PROCESS BY CONDENSING AN OXO COMPOUND WITH AN AMINO COMPOUND TO PRODUCE AN IMINE THEN REACTING WITH AN OXO QUINOLINE CARBOXYLIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |
| EP-0659178-A4 | CHIRAL QUINOLONE INTERMEDIATES. | ABBOTT LAB (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0659178-A1 | CHIRAL QUINOLONE INTERMEDIATES | ABBOTT LABORATORIES (US) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994006766-A1 | CHIRAL QUINOLONE INTERMEDIATES | ABBOTT LABORATORIES (US) | 1994-03-31 | — | — | WO | disclosed |
| US-5252747-A | Chiral quinolone intermediates | ABBOTT LABORATORIES (US) | 1993-10-12 | — | — | US | disclosed |
| US-5061712-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-29 | — | — | US | disclosed |
| EP-0401623-A1 | Process for the preparation of 7-(3-amino- and 3-aminomethyl-1-pyrrolidinyl)-3-quinolinonecarboxylic and -naphthyridinonecarboxylic acids | BAYER AG (DE) | 1990-12-12 | — | — | EP | disclosed |