Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535343 | 0.92 | AVPR1A (0.78) | AVPR1AAVPR2 | |
| SCHEMBL7338770 | 0.86 | AVPR1A (0.67) | AVPR1AAVPR2 | |
| SCHEMBL2938052 | 0.85 | AVPR1A (0.66) | AVPR1AAVPR2 | |
| SCHEMBL5782909 | 0.85 | AVPR1A (0.71) | AVPR1AAVPR2 | |
| SCHEMBL3536314 | 0.84 | AVPR1A (0.64) | AVPR1AAVPR2 | |
| SCHEMBL3553365 | 0.84 | AVPR1A (0.67) | AVPR1AAVPR2 | |
| SCHEMBL5118260 | 0.84 | AVPR1A (0.67) | AVPR1AAVPR2 | |
| SCHEMBL1344249 | 0.83 | AVPR1A (0.64) | AVPR1AAVPR2 | |
| SCHEMBL3554268 | 0.83 | AVPR1A (0.79) | AVPR1AAVPR2 | |
| SCHEMBL5117312 | 0.82 | AVPR1A (0.60) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687623-B2 | Pyrrolobenzodiazepines and heterocyclic carboxamide derivatives as follicle stimulating hormone receptor (FSH-R) antagonists | WYETH LLC (US) | 2010-03-30 | — | — | US | disclosed |
| US-20060258645-A1 | Pyrrolobenzodiazepines and heterocyclic carboxamide derivatives as follicle stimulating hormone receptor (FSH-R) antagonists | WYETH (US) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258645-A1 | Pyrrolobenzodiazepines and heterocyclic carboxamide derivatives as follicle stimulating hormone receptor (FSH-R) antagonists | FSHR, GNRHR, PRLHR | AVPR1A 16/4885AVPR2 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.