Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31304861 | 1.00 | GRIN2A (0.50) | GRIN2AGRIN2BGRIN2CKDM4EMEN1 | |
| SCHEMBL9250304 | 0.98 | KDM4E (0.49) | GRIN2AGRIN2BGRIN2CKDM4EMEN1 | |
| Lithium Ion SCHEMBL9250300 | 0.82 | MEN1 (0.48) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL9247059 | 0.82 | KDM4E (0.48) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL5369132 | 0.82 | GRIN2D (0.57) | GRIN2AGRIN2BGRIN2CKDM4EMEN1 | |
| SCHEMBL5353853 | 0.82 | GRIN2D (0.57) | GRIN2AGRIN2BGRIN2CKDM4EMEN1 | |
| SCHEMBL29434908 | 0.81 | CA12 (0.61) | GRIN2AGRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL124773 | 0.81 | CA12 (0.61) | GRIN2AGRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL216334 | 0.81 | CA12 (0.61) | GRIN2AGRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL569318 | 0.80 | KDM4E (0.65) | GRIN2AGRIN2BGRIN2CKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| EP-3561003-A1 | A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF | Clariant Plastics & Coatings Ltd (CH) | 2019-10-30 | — | — | EP | claimed |
| JP-59076292-A | — | — | None | — | — | JP | disclosed |
| WO-2025086591-A1 | ROTIGOTINE PRODRUG DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 烟台药物研究所 | 2025-05-01 | — | — | WO | disclosed |
| US-20250120987-A1 | METHOD FOR TREATING CANCER USING HUMAN MITOCHONDRIAL MALIC ENZYME 2 INHIBITOR | NATIONAL CHUNG HSING UNIVERSITY (TW) | 2025-04-17 | — | — | US | disclosed |
| US-20240424111-A1 | Degrader Compounds and Uses Thereof | CALICO LIFE SCIENCES LLC (US) | 2024-12-26 | — | — | US | disclosed |
| CN-119176787-A | Protein tyrosine phosphatase inhibitors, pharmaceutical compositions and uses thereof | 艾立康药业股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| US-20240383886-A1 | Protein Tyrosine Phosphatase Degraders and Methods of Use Thereof | ABBVIE INC. | 2024-11-21 | — | — | US | disclosed |
| CN-118894823-A | Naphthylamide compound serving as VEGFR inhibitor and application thereof | 重庆医科大学 | 2024-11-05 | — | — | CN | disclosed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| EP-4359409-A1 | DEGRADER COMPOUNDS AND USES THEREOF | Calico Life Sciences LLC (US) | 2024-05-01 | — | — | EP | disclosed |
| US-5426189-A | Dopamine receptor ligands and imaging agents | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-06-20 | — | — | US | disclosed |
| US-5334728-A | Dopamine receptor ligands and imaging agents | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0544495-A1 | Improved azo pigment compositions and process for their preparation | HOECHST CELANESE CORPORATION (US) | 1993-06-02 | — | — | EP | disclosed |
| US-5176750-A | Alkyl glycoside dispersant | HOECHST CELANESE CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| US-5066695-A | Plastics; heat resistance, dispersibility | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| JP-S5976292-A | FIXING TYPE HEAT SENSITIVE MATERIAL | MITSUBISHI PAPER MILLS LTD | 1984-05-01 | — | — | JP | disclosed |
| US-4115055-A | Mixture of water-insoluble monoazo dyestuffs for coloring textile materials consisting at least partly of linear, aromatic polyesters | ROHNER AG PRATTELN (CH) | 1978-09-19 | — | — | US | disclosed |
| US-4042704-A | FERTILITY CONTROL AGENTS | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | disclosed |
| US-3971741-A | DISPERSION PIGMENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383886-A1 | Protein Tyrosine Phosphatase Degraders and Methods of Use Thereof | PTPN5, PTPN1, PTPN2 | GRIN2A 4221/4885GRIN2B 4622/4885GRIN2C 3854/4885 |
| US-20240424111-A1 | Degrader Compounds and Uses Thereof | PTPN1, PTPN2, PTPN5 | GRIN2A 4232/4885GRIN2B 4535/4885GRIN2C 4102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.