Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 17/20 | 0.70 |
| ▸ | CDK1 | P06493 | 17/20 | 0.70 |
| ▸ | CCNB1 | P14635 | 15/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3596172 | 0.90 | AURKA (0.70) | AURKACDK1CCNB1CYP3A4CYP2C9 | |
| SCHEMBL3591999 | 0.89 | CDK1 (0.67) | AURKACDK1CCNB1CYP3A4CYP2C9 | |
| SCHEMBL3583517 | 0.89 | AURKA (0.70) | AURKACDK1CCNB1CYP3A4CYP2C9 | |
| SCHEMBL3591727 | 0.89 | AURKA (0.70) | AURKACDK1CCNB1CYP3A4CYP2C9 | |
| SCHEMBL3596118 | 0.84 | CDK1 (0.53) | AURKACDK1CCNB1CYP3A4CYP2C9 | |
| SCHEMBL1356175 | 0.82 | AURKA (1.00) | AURKACDK1CCNB1CYP3A4CYP2C9 | |
| SCHEMBL3583423 | 0.82 | AURKA (0.70) | AURKACDK1CCNB1CYP3A4CYP2C9 | |
| SCHEMBL3585958 | 0.80 | AURKA (0.50) | AURKACDK1CCNB1CYP3A4CYP2C9 | |
| SCHEMBL3571589 | 0.79 | AURKA (0.67) | AURKACDK1CCNB1CYP3A4CYP2C9 | |
| SCHEMBL3591802 | 0.78 | AURKA (0.68) | AURKACDK1CCNB1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4959 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108645905-B | A method of hydrogen peroxide is detected based on solid nano hole | 南通大学 | 2019-12-03 | — | — | CN | claimed |
| CN-110530839-A | The preparation method and its repeatable immune detection application of base material is immunized in a kind of molybdenum disulfide/silver nanoparticle | UNIV NINGBO | 2019-12-03 | — | — | CN | claimed |
| CN-110514711-A | The preparation method of renewable aptamer sensor based on automatically cleaning electrode interface | UNIV SHANDONG TECHNOLOGY | 2019-11-29 | — | — | CN | claimed |
| CN-110511386-A | Double property macromolecules and its manufacturing method include the high molecular contact lens material of this double property and its manufacturing method | UNIV NATIONAL CHIAO TUNG | 2019-11-29 | — | — | CN | claimed |
| CN-110498886-A | A kind of lubricating hydrogel material and its preparation method and application | UNIV JILIN | 2019-11-26 | — | — | CN | claimed |
| CN-110483662-A | A kind of carboxymethyl chitosan cross-linked gel | UNIV CHANGZHOU | 2019-11-22 | — | — | CN | claimed |
| CN-110483804-A | Modified biopolymer and its application in 3D printing | SHENZHEN INST ADV TECH | 2019-11-22 | — | — | CN | claimed |
| CN-110483845-A | A kind of graphene oxide/chitosan oligosaccharide composite crosslinking gel | UNIV CHANGZHOU | 2019-11-22 | — | — | CN | claimed |
| CN-110470718-A | It is a kind of for detecting the preparation method of the optical electro-chemistry immunosensor of cardiac muscle troponin I | UNIV JINAN | 2019-11-19 | — | — | CN | claimed |
| CN-110448735-A | A kind of amphiphilic biology carbon complex and its preparation method and purposes with antibiosis anticoagulative | ZHENGZHOU OUMUKANG BIOMATERIAL CO LTD | 2019-11-15 | — | — | CN | claimed |
| CN-101011596-A | Process for preparing antibiotic-peptide modified-fibroin film material | UNIV ZHEJIANG SCIENCE & TECH (CN) | 2007-08-08 | — | — | CN | claimed |
| CN-1943791-A | Liver target high molecule magnetic resonance image-forming contrast medium and its synthesizing method and application | UNIV HUADONG (CN) | 2007-04-11 | — | — | CN | claimed |
| CN-1910143-A | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD (US) | 2007-02-07 | — | — | CN | claimed |
| CN-1910144-A | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD (US) | 2007-02-07 | — | — | CN | claimed |
| CN-1856486-A | Substituted lactams and their use as anti-cancer agents | NOVARTIS AG (CH) | 2006-11-01 | — | — | CN | claimed |
| CN-1660884-A | Anthraquinone ramification of rhubarb, preparing method and combination of medication by using the ramification as active ingredient | MEDICAL COLLEGE OF PEOPLE S AR (CN) | 2005-08-31 | — | — | CN | claimed |
| US-20050048551-A1 | Analyte evaluating device, method for evaluating analyte and method for manufacturing analyte evaluating device | FUJITSU LIMITED (JP) | 2005-03-03 | — | — | US | claimed |
| CN-1271352-A | Process for preparing 3-aryloxy, 4-arylfuran-2-ones useful as cyclooxygenase-2 inhibitors | MERCK & CO INC (US) | 2000-10-25 | — | — | CN | claimed |
| CN-1224426-A | 3-descladinose-2, 3-anhydroerythromycin derivatives | ABBOTT LAB (US) | 1999-07-28 | — | — | CN | claimed |
| CN-1035253-C | Pyranyl cyanoguanidine derivatives | SQUIBB & SONS INC (US) | 1997-06-25 | — | — | CN | claimed |