Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 6/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.42 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175871 | 0.90 | BCHE (0.49) | KDM4ECNR1MEN1KMT2ABCHE | |
| SCHEMBL3272263 | 0.88 | KDM4E (0.50) | KDM4ECNR1MEN1KMT2ABCHE | |
| SCHEMBL3581357 | 0.88 | KMT2A (0.61) | KDM4EMEN1KMT2ABCHECHRM2 | |
| SCHEMBL3387196 | 0.82 | BCHE (0.49) | KDM4ECNR1MEN1KMT2ABCHE | |
| SCHEMBL3581270 | 0.82 | BCHE (0.52) | KDM4ECNR1MEN1KMT2ABCHE | |
| SCHEMBL3574201 | 0.82 | KDM4E (0.55) | KDM4ECNR1MEN1KMT2ASCN8A | |
| SCHEMBL9957662 | 0.81 | CNR1 (0.49) | KDM4ECNR1MEN1KMT2ABCHE | |
| SCHEMBL5176588 | 0.81 | CNR1 (0.46) | KDM4ECNR1MEN1KMT2ABCHE | |
| SCHEMBL5175899 | 0.80 | KDM4E (0.58) | KDM4ECNR1MEN1KMT2ABCHE | |
| SCHEMBL5227133 | 0.80 | CETP (0.50) | KDM4ECNR1MEN1KMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |