Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.78 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12115014 | 0.82 | CES1 (0.78) | CES1ESR2BCHEACHECES2 | |
| SCHEMBL31237486 | 0.82 | CES1 (0.78) | CES1ESR2BCHEACHECES2 | |
| SCHEMBL3580678 | 0.69 | CES1 (0.59) | CES1ESR2BCHEACHEPOLB | |
| SCHEMBL3584746 | 0.69 | CES1 (0.59) | CES1ESR2BCHEACHEPOLB | |
| SCHEMBL29314362 | 0.68 | CES1 (0.55) | CES1ESR2BCHEACHECES2 | |
| SCHEMBL3585903 | 0.68 | CES1 (0.48) | CES1ESR2BCHEACHECES2 | |
| SCHEMBL12433609 | 0.67 | CYP1A2 (0.59) | CES1ESR2BCHEACHECES2 | |
| SCHEMBL2607400 | 0.65 | CYP2A6 (0.48) | CES1ACHECES2KDM1AEED | |
| SCHEMBL24534291 | 0.64 | CYP1A2 (0.54) | CES1ESR2BCHEACHECES2 | |
| SCHEMBL3584662 | 0.64 | CES1 (0.53) | CES1ESR2BCHEACHEESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104983738-B | Improve the pharmaceutical composition of platelet aggregation and its screening technique using PTAFR as target spot | 安徽科技学院 | 2018-05-08 | — | — | CN | claimed |
| CN-105055516-A | New anti-inflammatory medicine with bone protection function and composed of glucocorticoid and salvia extract | GUANGDONG MEDICAL COLLEGE | 2015-11-18 | — | — | CN | claimed |
| CN-104983738-A | Pharmaceutical composition for improving platelet aggregation, and pharmaceutical composition screening method adopting PTAFR as target point | UNIV ANHUI SCIENCE & TECH | 2015-10-21 | — | — | CN | claimed |
| CN-111979191-B | Method for enhancing killing power of CIK (cytokine induced killer) cells, CIK cells and application | 郑州源创基因科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-111979191-A | Method for enhancing killing power of CIK (cytokine induced killer) cells, CIK cells and application | 单海华 | 2020-11-24 | — | — | CN | disclosed |
| CN-108276420-B | 8, 13-dihydrobenzo [5,6] chromene [2,3-b ] indole compound and synthetic method thereof | 四川理工学院 | 2020-11-24 | — | — | CN | disclosed |
| CN-110249932-A | A kind of method of Chinese prescription Cultivated rapeseed | 梁平县高板桥水稻种植专业合作社 | 2019-09-20 | — | — | CN | disclosed |
| CN-109908323-A | A kind of compound product production method facilitated human bone marrow's stem cell regenerating and activate suspend mode stem cell | 李胜 | 2019-06-21 | — | — | CN | disclosed |
| CN-105581965-B | Conditioning-type women private portion conditioning liquid is sterilized in nutrition | 南京瑞霖松生物科技有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-106565691-B | Benzo coumarin derivatives pharmaceutically acceptable salt and its preparation method and application | 浙江工业大学 | 2019-02-22 | — | — | CN | disclosed |
| CN-109297929-A | A method of salvia piece quality grading is established using near infrared technology | 国药集团同济堂（贵州）制药有限公司 | 2019-02-01 | — | — | CN | disclosed |
| EP-1722779-A4 | NEO-TANSHINLACTONE AND ANALOGS AS POTENT AND SELECTIVE ANTI-BREAST CANCER AGENTS | UNIV NORTH CAROLINA (US) | 2009-05-06 | — | — | EP | disclosed |
| US-7495026-B2 | Neo-tanshinlactone and analogs as potent and selective anti-breast cancer agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-02-24 | — | — | US | disclosed |
| US-7495026-B2 | Neo-tanshinlactone and analogs as potent and selective anti-breast cancer agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-02-24 | — | — | US | disclosed |
| EP-1722779-A1 | NEO-TANSHINLACTONE AND ANALOGS AS POTENT AND SELECTIVE ANTI-BREAST CANCER AGENTS | The University of North Carolina at Chapel Hill (US) | 2006-11-22 | — | — | EP | disclosed |
| US-20050250751-A1 | Neo-tanshinlactone and analogs as potent and selective anti-breast cancer agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-11-10 | — | — | US | disclosed |
| WO-2005087225-A1 | NEO-TANSHINLACTONE AND ANALOGS AS POTENT AND SELECTIVE ANTI-BREAST CANCER AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050181080-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2005-08-18 | — | — | US | disclosed |
| US-20030165533-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2003-09-04 | — | — | US | disclosed |
| US-20030152588-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250751-A1 | Neo-tanshinlactone and analogs as potent and selective anti-breast cancer agents | BRCA1, CYP19A1, CYP51A1 | CES1 1629/4885ESR2 54/4885BCHE 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.