⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566395 | 1.00 | — | — | |
| SCHEMBL9566469 | 1.00 | — | — | |
| SCHEMBL9566390 | 1.00 | — | — | |
| SCHEMBL9566372 | 1.00 | — | — | |
| SCHEMBL12274704 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9566502 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL9566367 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL9566377 | 0.97 | — | — | |
| Bromide SCHEMBL9572069 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL9566386 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | claimed |
| JP-7300460-A | — | — | None | — | — | JP | disclosed |
| WO-2021262426-A2 | ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2021-12-30 | — | — | WO | disclosed |
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |
| US-20200187502-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-18 | — | — | US | disclosed |
| WO-2018162643-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-13 | — | — | WO | disclosed |
| EP-2686320-B1 | TRICYCLIC GYRASE INHIBITORS | MERCK SHARP & DOHME (US) | 2016-05-18 | — | — | EP | disclosed |
| WO-2012125746-A1 | TRICYCLIC GYRASE INHIBITORS | TRIUS THERAPEUTICS INC. (US) | 2012-09-20 | — | — | WO | disclosed |
| WO-2011032050-A2 | GYRASE INHIBITORS | TRIUS THERAPEUTICS, INC. (US) | 2011-03-17 | — | — | WO | disclosed |
| US-20100069435-A1 | METHOD OF SELECTIVELY INTRODUCING AMINO SUBSTITUENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-7626029-B2 | Into a difluorobenzoic acid, for producting quinolonecarboxylic acid serving as synthetic antibacterial agent, medicament, agricultural chemical, or veterinary drug; ionic liquid solvents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-12-01 | — | — | US | disclosed |
| US-20060122396-A1 | Method of selectively introducing amino substituent | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-06-08 | — | — | US | disclosed |
| EP-1634879-A1 | METHOD OF SELECTIVELY INTRODUCING AMINO SUBSTITUENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-0816355-B1 | HETEROCYCLIC SPIRO DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6469023-B1 | QUINOLONE DERIVATIVE HAVING A 1-AMINO-5- AZABISPIRO(2.4)HEPTYL GROUP AT THE 7-POSITION AND A HALOGENOCYCLOPROPYL GROUP AT THE 1-POSITION; AN ANTIBACTERIAL COMPOUND USEFUL AS MEDICINES, ANIMAL DRUGS, FISHERIES DRUGS OR ANTIBACTERIAL PRESERVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0816355-A1 | HETEROCYCLIC SPIRO DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-01-07 | — | — | EP | disclosed |
| JP-H07300460-A | NEW AZASPIRO DERIVATIVE AND ITS PRODUCTION | KOREA RES INST CHEM TECHNOL | 1995-11-14 | — | — | JP | disclosed |
| EP-0550016-A1 | Novel quinolone carboxylic acid derivatives and processes for preparing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |