⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850012 | 0.79 | DAO (0.37) | — | |
| SCHEMBL22494215 | 0.77 | — | — | |
| SCHEMBL329181 | 0.77 | — | — | |
| SCHEMBL31655499 | 0.75 | — | — | |
| SCHEMBL736923 | 0.75 | — | — | |
| SCHEMBL3663031 | 0.75 | — | — | |
| SCHEMBL3578021 | 0.75 | — | — | |
| SCHEMBL1259253 | 0.75 | — | — | |
| Benzene SCHEMBL28468895 | 0.73 | TSHR (0.42) | — | |
| Hydrochloric Acid SCHEMBL27659745 | 0.73 | DAO (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022205586-A1 | PREPARATION METHOD FOR PYRROLE-2-SULFONAMIDE COMPOUND AND APPLICATION THEREOF IN PREPARING ANTI-TUMOR DRUG | 苏州大学 | 2022-10-06 | — | — | WO | claimed |
| CN-113069451-B | Preparation method of pyrrole-2-sulfonamide compound and application of pyrrole-2-sulfonamide compound in preparation of antitumor drugs | 苏州大学 | 2022-08-09 | — | — | CN | claimed |
| CN-113069451-A | Preparation method of pyrrole-2-sulfonamide compound and application of pyrrole-2-sulfonamide compound in preparation of antitumor drugs | 苏州大学 | 2021-07-06 | — | — | CN | claimed |
| WO-2022205586-A1 | PREPARATION METHOD FOR PYRROLE-2-SULFONAMIDE COMPOUND AND APPLICATION THEREOF IN PREPARING ANTI-TUMOR DRUG | 苏州大学 | 2022-10-06 | — | — | WO | disclosed |
| CN-113069451-B | Preparation method of pyrrole-2-sulfonamide compound and application of pyrrole-2-sulfonamide compound in preparation of antitumor drugs | 苏州大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-113069451-A | Preparation method of pyrrole-2-sulfonamide compound and application of pyrrole-2-sulfonamide compound in preparation of antitumor drugs | 苏州大学 | 2021-07-06 | — | — | CN | disclosed |
| EP-3558981-A1 | PYRAN DERVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS | Orion Corporation (FI) | 2019-10-30 | — | — | EP | disclosed |
| CN-110312716-A | Bicyclic OGA inhibitor compound | 詹森药业有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-108602820-A | Hetero-1, 5,6, 7-tetrahydro-4H-indol-4-ones | 拜耳制药股份公司 | 2018-09-28 | — | — | CN | disclosed |
| WO-2018115591-A1 | PYRAN DERVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS | ORION CORPORATION (FI) | 2018-06-28 | — | — | WO | disclosed |
| CN-105384725-B | Preparation method and application of azimsulfuron key intermediate | 江西安利达化工有限公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-1997363-A | Resistance-repellent retroviral protease inhibitors | SEQUOIA PHARMACEUTICALS (US) | 2007-07-11 | — | — | CN | disclosed |
| US-7238720-B2 | Pharmaceutical use of N-carbamoylazole derivatives | EISAI R & D MANAGEMENT CO. LTD. (JP) | 2007-07-03 | — | — | US | disclosed |
| EP-1258480-B1 | Pharmaceutical use of N-Carbamoylazole derivatives | EISAI CO LTD (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-20040186153-A1 | Pharmaceutical use of N-carbamoylazole derivatives | EISAI R & D MANAGEMENT CO. LTD. (JP) | 2004-09-23 | — | — | US | disclosed |
| US-20030060494-A1 | Pharmaceutical use of N-carbamoylazole derivatives | EISAI CO., LTD. (JP) | 2003-03-27 | — | — | US | disclosed |
| EP-1258480-A1 | Pharmaceutical use of N-Carbamoylazole derivatives | Eisai Co., Ltd. (JP) | 2002-11-20 | — | — | EP | disclosed |
| CN-1057305-C | Estra-1,3,5 (10)-triene derivatives, methods of preparing such compounds and pharmaceutical compositions containing them | JENAPHARM GMBH (DE) | 2000-10-11 | — | — | CN | disclosed |
| CN-1160404-A | Pharmaceutical compositions contg. estra-1,3,5C10-triene derivs. | JENAPHARM GMBH (DE) | 1997-09-24 | — | — | CN | disclosed |
| CN-1156998-A | Estra-1, 3, 5(10) -triene derivatives, process for their preparation and pharmaceutical compositions containing them | JENAPHARM GMBH (DE) | 1997-08-13 | — | — | CN | disclosed |