⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3204317 | 0.75 | — | — | |
| SCHEMBL1431301 | 0.70 | — | — | |
| SCHEMBL6965318 | 0.69 | — | — | |
| SCHEMBL8570825 | 0.69 | — | — | |
| SCHEMBL27613896 | 0.69 | — | — | |
| SCHEMBL27291010 | 0.67 | — | — | |
| SCHEMBL28273402 | 0.67 | — | — | |
| SCHEMBL6965316 | 0.67 | — | — | |
| SCHEMBL970099 | 0.67 | — | — | |
| SCHEMBL3204309 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126181-A | Trifluoromethyl phenylthiourea-quinoline copper complex with tumor autophagy induction effect, and preparation method and application thereof | 河南城建学院 | 2023-11-28 | — | — | CN | disclosed |
| CN-115449136-A | Accelerator composition of rubber nanocomposite and preparation method and application thereof | 浙江大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-113924669-A | Copper foil preventing occurrence of wrinkles, electrode including the same, secondary battery including the same, and method of manufacturing the same | SK纳力世有限公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-104870449-B | Compound (I) | 奇斯药制品公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-105295011-B | Preparation method of poly alpha-hydroxy acid | 南京工业大学 | 2017-11-07 | — | — | CN | disclosed |
| CN-107098895-A | Phenylamino thiazole methyl qualone derivative and preparation method and application | 湖南大学 | 2017-08-29 | — | — | CN | disclosed |
| CN-106459065-A | Tetrahydrotriazolopyrimidine derivatives, pharmaceutical compositions containing the same and uses | 奇斯药制品公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106459054-A | Novel compounds | 奇斯药制品公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-103827117-B | Tetrahydrochysene triazolopyrimidine derivative as people's inhibitors of neutrophil elastase | 奇斯药制品公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105873933-A | Tetrahydrotriazolopyrimidine derivatives as human neutrophil elastase inhibitors | 奇斯药制品公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-104870449-A | Novel compounds | CHIESI FARMA SPA | 2015-08-26 | — | — | CN | disclosed |
| CN-102603726-B | 5-(2-aminothiazole-4-yl) benzofuranol etheric compound with herbicidal activity and preparation method | HUNAN RES INST CHEMICAL IND | 2014-08-13 | — | — | CN | disclosed |
| CN-103827117-A | Tetrahydrotriazolopyrimidine derivatives as human neutrophil elastase inhibitors | CHIESI FARMA SPA | 2014-05-28 | — | — | CN | disclosed |
| CN-102603726-A | 5-(2-aminothiazole-4-yl) benzofuranol etheric compound with herbicidal activity and preparation method | HUNAN RES INST CHEMICAL IND | 2012-07-25 | — | — | CN | disclosed |
| CN-102010406-B | 4-(benzofuran-5-yl)-2-aromatic aminothiazole and preparation method and application thereof | UNIV HUNAN | 2012-07-04 | — | — | CN | disclosed |
| CN-102010406-A | 4-(benzofuran-5-yl)-2-aromatic aminothiazole and preparation method and application thereof | UNIV HUNAN | 2011-04-13 | — | — | CN | disclosed |
| US-20100048641-A1 | Use of Adenosine A1 and/or Dual A1/2ab Agonists for Production of Medicaments for Treating Diseases | BAYER HEALTHCARE AG LAW AND PATENTS,PATENTS AND LICENSING (DE) | 2010-02-25 | — | — | US | disclosed |
| CN-101636155-A | Inhibitors of diacylglycerol O-acyltransferase type 1 enzyme | ABBOTT LAB | 2010-01-27 | — | — | CN | disclosed |
| US-20080269300-A1 | Substituted Phenylaminothiazoles and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-5739336-A | SELECTIVE 5-HYDROXYTRYPTAMINE-2C RECEPTOR ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1998-04-14 | — | — | US | disclosed |