Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 14/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3597065 | 0.87 | EPAS1 (0.41) | GCKPTGS2 | |
| SCHEMBL1262231 | 0.81 | MEN1 (0.46) | GCKKMT2AMEN1PTGS2 | |
| SCHEMBL3588747 | 0.80 | GCK (0.50) | GCKKMT2AMEN1 | |
| SCHEMBL3601976 | 0.78 | KMT2A (0.41) | KMT2AMEN1 | |
| SCHEMBL1107719 | 0.76 | MEN1 (0.58) | GCKKMT2AMEN1PTGS2 | |
| SCHEMBL1528289 | 0.76 | GCK (0.63) | GCKKMT2AMEN1PTGS2 | |
| SCHEMBL1107636 | 0.72 | GCK (0.66) | GCKKMT2AMEN1PTGS2 | |
| SCHEMBL1107571 | 0.72 | GCK (0.41) | GCKKMT2AMEN1PTGS2PTGES | |
| SCHEMBL2654925 | 0.71 | MEN1 (0.49) | GCKKMT2AMEN1PTGS2 | |
| SCHEMBL1107611 | 0.71 | MEN1 (0.52) | GCKKMT2AMEN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700640-B2 | Process for making phenoxy benzamide compounds | ASTRAZENECA AB (SE) | 2010-04-20 | — | — | US | disclosed |
| US-20080200694-A1 | Process for Making Phenoxy Benzamide Compounds | ASTRAZENECA AB (SE) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200694-A1 | Process for Making Phenoxy Benzamide Compounds | PAH, MAOB, TYR | GCK 1415/4885KMT2A 726/4885MEN1 2346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.