SCHEMBL3589836

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3591217	0.88	APP (0.77)	APPEGFRCDK1KDRIGF1R
	SCHEMBL14753415	0.88	APP (0.76)	APPCCNA2CDK2CDK5CDK5R1
	SCHEMBL3598097	0.86	APP (0.74)	APPSYKEGFRKDRMEN1
	SCHEMBL3602388	0.86	APP (1.00)	APPSYK
	SCHEMBL3651837	0.85	APP (0.57)	APPSYKEGFRMEN1KMT2A
	SCHEMBL4552735	0.82	APP (0.53)	APPSYKCCNA2CDK2CDK5
	SCHEMBL3583812	0.81	SYK (0.61)	APPSYKCCNA2CDK2CDK5
	SCHEMBL3607808	0.80	APP (0.72)	APPSYKCCNA2CDK2CDK5
	SCHEMBL20838956	0.78	SMN1; SMN2 (0.55)	APPMEN1KMT2ACYP3A4RAB9A
	SCHEMBL30053811	0.78	SMN1; SMN2 (0.55)	APPMEN1KMT2ACYP3A4RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.