Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | DCUN1D1 | Q96GG9 | 12/20 | 0.54 |
| ▸ | UBE2M | P61081 | 11/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10108279 | 0.92 | DCUN1D1 (0.56) | ALDH1A1DCUN1D1UBE2MLMNAMAPT | |
| SCHEMBL549026 | 0.81 | DCUN1D1 (0.64) | DCUN1D1UBE2MCASR | |
| SCHEMBL5126613 | 0.81 | DCUN1D1 (0.62) | DCUN1D1UBE2MCASR | |
| SCHEMBL4676983 | 0.80 | CASR (0.63) | POLBDCUN1D1UBE2MMAPTCASR | |
| SCHEMBL549106 | 0.80 | DCUN1D1 (0.60) | DCUN1D1UBE2MCASR | |
| SCHEMBL548245 | 0.80 | DCUN1D1 (0.58) | DCUN1D1UBE2MCASR | |
| SCHEMBL548234 | 0.78 | DCUN1D1 (0.72) | POLBDCUN1D1UBE2MCASR | |
| SCHEMBL548246 | 0.76 | DCUN1D1 (0.55) | DCUN1D1UBE2MCASR | |
| SCHEMBL18640247 | 0.70 | DCUN1D1 (1.00) | DCUN1D1UBE2M | |
| SCHEMBL18640257 | 0.70 | DCUN1D1 (1.00) | DCUN1D1UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858789-B2 | Derivatives of 4-aminopiperidine and their use as a medicament | IPSEN PHARMA S.A.S. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-7858789-B2 | Derivatives of 4-aminopiperidine and their use as a medicament | IPSEN PHARMA S.A.S. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-7858789-B2 | Derivatives of 4-aminopiperidine and their use as a medicament | IPSEN PHARMA S.A.S. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-20090149652-A1 | Derivatives of 4-aminopiperidine and their use as a medicament | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES | 2009-06-11 | — | — | US | disclosed |
| US-20090149652-A1 | Derivatives of 4-aminopiperidine and their use as a medicament | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES | 2009-06-11 | — | — | US | disclosed |
| US-20090149652-A1 | Derivatives of 4-aminopiperidine and their use as a medicament | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES | 2009-06-11 | — | — | US | disclosed |
| US-7393861-B2 | Derivatives of 4-aminopiperidine and their use as a medicament | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2008-07-01 | — | — | US | disclosed |
| US-7393861-B2 | Derivatives of 4-aminopiperidine and their use as a medicament | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2008-07-01 | — | — | US | disclosed |
| US-7115634-B2 | 4-aminopiperidine and their use as a medicine | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2006-10-03 | — | — | US | disclosed |
| US-20040006089-A1 | 4-Aminopiperidine and their use as a medicine | IPSEN PHARMA S.A.S. (FR) | 2004-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149652-A1 | Derivatives of 4-aminopiperidine and their use as a medicament | SSTR4, SSTR3, SSTR1 | HCRTR1 312/4885HCRTR2 354/4885TSHR 52/4885 |
| US-20040006089-A1 | 4-Aminopiperidine and their use as a medicine | SSTR1, SSTR2, SSTR4 | HCRTR1 340/4885HCRTR2 324/4885TSHR 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.