SCHEMBL3590767

SCHEMBL3590767

NC(CCc1ccccc1)[C@H](C(=O)O)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
FABP5 Q01469 3/20 0.43
FABP7 O15540 2/20 0.43
METAP2 P50579 1/20 0.41
METAP1 P53582 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
EPHX2 P34913 1/20 0.39
OPRD1 P41143 1/20 0.38
MDM4 O15151 1/20 0.38
TP53 P04637 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
CASP3 P42574 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2320540 0.89 MDM2 (0.44) KMT2AFABP5FABP7EPHX2
SCHEMBL29036117 0.88 KMT2A (0.45) KMT2AFABP5FABP7CA1CA2
SCHEMBL7128599 0.85 KMT2A (0.47) KMT2AFABP5FABP7CA1CA2
SCHEMBL28888234 0.84 KMT2A (0.46) KMT2AFABP5FABP7CA1CA2
SCHEMBL7389338 0.82 KMT2A (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL7391410 0.82 KMT2A (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL7119225 0.82 KMT2A (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL7393490 0.82 KMT2A (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL28215432 0.81 KMT2A (0.48) KMT2AFABP5FABP7CA1CA2
SCHEMBL1296654 0.81 KMT2A (0.43) KMT2AFABP5FABP7CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed
EP-1885693-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 Wurster, Siegfried (FI) 2008-02-13 EP disclosed
WO-2006123020-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 JUVANTIA PHARMA LTD OY (FI) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 KMT2A 2996/4885FABP5 1843/4885FABP7 963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.