⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860907 | 0.84 | — | — | |
| SCHEMBL155526 | 0.82 | — | — | |
| SCHEMBL19192740 | 0.79 | — | — | |
| SCHEMBL18762858 | 0.77 | — | — | |
| SCHEMBL4165805 | 0.76 | — | — | |
| SCHEMBL6693717 | 0.74 | — | — | |
| SCHEMBL15741719 | 0.72 | — | — | |
| Tetrahydrofuran-3-Carbaldehyde SCHEMBL21581981 | 0.72 | — | — | |
| SCHEMBL1255621 | 0.72 | — | — | |
| SCHEMBL19045382 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204407-B1 | PROCESS | GIVAUDAN SA (CH) | 2024-06-19 | — | — | EP | claimed |
| US-20230312506-A1 | PROCESS | GIVAUDAN SA (CH) | 2023-10-05 | — | — | US | claimed |
| US-20230227449-A1 | AMIDOPYRIMIDONE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-07-20 | — | — | US | claimed |
| EP-4204407-A1 | PROCESS | Givaudan SA (CH) | 2023-07-05 | — | — | EP | claimed |
| CN-116209659-A | Method | 奇华顿股份有限公司 | 2023-06-02 | — | — | CN | claimed |
| CN-115867541-A | Aminopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-03-28 | — | — | CN | claimed |
| EP-1448218-A4 | BETA-SECRETASE INHIBITORS AND METHODS OF USE | OKLAHOMA MED RES FOUND (US) | 2009-01-14 | — | — | EP | claimed |
| EP-1448218-A2 | BETA-SECRETASE INHIBITORS AND METHODS OF USE | Oklahoma Medical Research Foundation (US) | 2004-08-25 | — | — | EP | claimed |
| WO-2003039454-A2 | BETA-SECRETASE INHIBITORS AND METHODS OF USE | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2003-05-15 | — | — | WO | claimed |
| EP-4204407-B1 | PROCESS | GIVAUDAN SA (CH) | 2024-06-19 | — | — | EP | disclosed |
| US-20240139087-A1 | ORGANIC COMPOUNDS AS TRPM8 ACTIVATORS | GIVAUDAN SA (CH) | 2024-05-02 | — | — | US | disclosed |
| US-20240132487-A1 | SUBSTITUTED AZACYLES AS TRMP8 MODULATORS | GIVAUDAN SA (CH) | 2024-04-25 | — | — | US | disclosed |
| EP-4291553-A1 | ORGANIC COMPOUNDS AS TRPM8 ACTIVATORS | Givaudan SA (CH) | 2023-12-20 | — | — | EP | disclosed |
| EP-3901147-B1 | ACYLAMINO BRIDGED HETEROCYCLIC COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2023-11-22 | — | — | EP | disclosed |
| US-20080214620-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-09-04 | — | — | US | disclosed |
| WO-2008065141-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-06-05 | — | — | WO | disclosed |
| WO-2008000645-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-01-03 | — | — | WO | disclosed |
| US-20080004442-A1 | Tetrazole-substituted arylamides as P2X3 and P2X2/3 antagonists | ROCHE PALO ALTO LLC | 2008-01-03 | — | — | US | disclosed |
| US-4335138-A | HYPNOTIC, SEDATIVE | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |
| EP-0026369-A2 | Carbamates, their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-04-08 | — | — | EP | disclosed |