Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 19/20 | 0.52 |
| ▸ | CHUK | O15111 | 17/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3592437 | 1.00 | IKBKB (0.52) | IKBKBCHUKSCN9A | |
| SCHEMBL13440391 | 1.00 | IKBKB (0.52) | IKBKBCHUKSCN9A | |
| SCHEMBL3602243 | 0.92 | IKBKB (0.58) | IKBKBCHUK | |
| SCHEMBL3602238 | 0.92 | IKBKB (0.58) | IKBKBCHUK | |
| SCHEMBL3596713 | 0.91 | IKBKB (0.64) | IKBKBCHUK | |
| SCHEMBL3596718 | 0.91 | IKBKB (0.64) | IKBKBCHUK | |
| SCHEMBL13440390 | 0.91 | IKBKB (0.64) | IKBKBCHUK | |
| SCHEMBL3594587 | 0.90 | IKBKB (0.65) | IKBKBCHUK | |
| SCHEMBL3594591 | 0.90 | IKBKB (0.65) | IKBKBCHUK | |
| SCHEMBL3596347 | 0.90 | IKBKB (0.65) | IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069417-A1 | NOVEL PHENYL(4-PHENYLPYRIMIDIN-2-YL)AMINE DERIVATIVES, THEIR PREPARATION, AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS IKK INHIBITORS | SANOFI-AVENTIS (FR) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069417-A1 | NOVEL PHENYL(4-PHENYLPYRIMIDIN-2-YL)AMINE DERIVATIVES, THEIR PREPARATION, AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS IKK INHIBITORS | IKBKB, NFKBIA, IKBKE | IKBKB 1/4885CHUK 4/4885SCN9A 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.