SCHEMBL3592850

SCHEMBL3592850

[SiH3]OCCCOCC1CO1

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.71
SMN1; SMN2 Q16637 2/20 0.61
ALDH1A1 P00352 5/20 0.57
TDP1 Q9NUW8 2/20 0.57
MAPK1 P28482 1/20 0.42
TP53 P04637 2/20 0.33
CYP3A4 P08684 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29055679 0.98 TSHR (0.68) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL150451 0.96 TSHR (0.78) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL10401328 0.94 TSHR (0.75) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1948806 0.94 TSHR (0.75) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL24547426 0.89 TSHR (0.90) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL100304 0.89 TSHR (0.90) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1937296 0.86
SCHEMBL8958435 0.86 TSHR (0.85) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL15358765 0.86 TSHR (0.85) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL13433071 0.84 TSHR (0.81) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7692013-B2 Method for separation and purification of hydrocodone by preparative chromatography MALLINKRODT INC. (US) 2010-04-06 US claimed
EP-1682505-B1 INDUSTRIAL METHOD FOR SEPARATION AND PURIFICATION OF FENTANYL BY REVERSE PHASE PREPARATIVE CHROMATOGRAPHY MALLINCKRODT INC (US) 2008-12-24 EP claimed
CN-120082260-A Micro-LED laser massive transfer release material and preparation method and application thereof 深圳市化讯半导体材料有限公司 2025-06-03 CN disclosed
CN-117924833-A High-performance composite material and application thereof 中建八局第三建设有限公司 2024-04-26 CN disclosed
EP-4219579-A1 PREPARATION OF ALIPHATIC POLYURETHANE SOFT FOAMS IN A PREPOLYMER PROCESS BASED ON ALIPHATIC OLIGOMERIC POLYISOCYANATES AND MONOHYDROXY-FUNCTIONAL COMPOUNDS Covestro Deutschland AG (DE) 2023-08-02 EP disclosed
US-20230174734-A1 THERMALLY EXPANDABLE MICROSPHERES PREPARED FROM BIO-BASED MONOMERS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2023-06-08 US disclosed
US-20230148347-A1 THERMALLY EXPANDABLE MICROSPHERES PREPARED FROM BIO-BASED MONOMERS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2023-05-11 US disclosed
EP-4126334-A1 THERMALLY EXPANDABLE MICROSPHERES PREPARED FROM BIO-BASED MONOMERS Nouryon Chemicals International B.V. (NL) 2023-02-08 EP disclosed
EP-4126333-A1 THERMALLY EXPANDABLE MICROSPHERES PREPARED FROM BIO-BASED MONOMERS Nouryon Chemicals International B.V. (NL) 2023-02-08 EP disclosed
WO-2021198487-A1 THERMALLY EXPANDABLE MICROSPHERES PREPARED FROM BIO-BASED MONOMERS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2021-10-07 WO disclosed
WO-2021198492-A1 THERMALLY EXPANDABLE MICROSPHERES PREPARED FROM BIO-BASED MONOMERS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2021-10-07 WO disclosed
US-20080116800-A1 PLASMA DISPLAY PANEL, METHOD FOR MANUFACTURING THE SAME, AND RELATED TECHNOLOGIES LG ELECTRONICS INC. (KR) 2008-05-22 US disclosed
EP-0567830-B1 A method of modifying lipases NESTLE SA (CH) 2000-03-08 EP disclosed
EP-0470247-B1 REVERSED PHASE CHROMATOGRAPHIC PROCESS MALLINCKRODT INC (US) 1997-04-16 EP disclosed
US-5384256-A Pectin-modified lipase from Mucor javanicus with lowered saturated/unsaturated fatty acid ratio NESTEC S.A. (CH) 1995-01-24 US disclosed
EP-0341322-B1 Polyether end-blocked with hydrolyzable silyl groups, method of manufacturing and room temperature curable composition using the polyether TOSHIBA SILICONE (JP) 1993-12-22 EP disclosed
EP-0567830-A1 Modified lipase, method of modification and applications SOCIETE DES PRODUITS NESTLE S.A. (CH) 1993-11-03 EP disclosed
EP-0567661-A1 Modified lipase, method of modification and applications SOCIETE DES PRODUITS NESTLE S.A. (CH) 1993-11-03 EP disclosed
US-4873272-A Polyether end-blocked with hydrolyzable silyl groups, method of manufacturing and room temperature curable composition using the polyether TOSHIBA SILICONE CO., LTD. (JP) 1989-10-10 US disclosed
US-4847357-A WEATHERPROOFING, HEAT RESISTANT SEALS TOSHIBA SILICONE CO., LTD. (JP) 1989-07-11 US disclosed