SCHEMBL3593101

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3588577	0.93	COMT (0.55)	COMTERN1NPC1RAB9ATTR
	SCHEMBL3594046	0.88	COMT (0.46)	COMTNPC1RAB9AMAPTHPGD
	SCHEMBL3590661	0.85	COMT (0.41)	COMTERN1RAB9ATTRMAPT
	SCHEMBL3596419	0.84	COMT (0.47)	COMTNPC1RAB9ATTRMAPT
	SCHEMBL1446844	0.83	COMT (0.56)	COMTERN1NPC1RAB9ATTR
	SCHEMBL3586890	0.83	COMT (0.42)	COMTERN1NPC1RAB9ATTR
	SCHEMBL3586674	0.83	COMT (0.38)	COMTERN1TTRMAPTHPGD
	SCHEMBL3577373	0.83	COMT (0.38)	COMTERN1TTRMAPTHPGD
	SCHEMBL3584737	0.82	COMT (0.48)	COMTERN1NPC1RAB9ATTR
	SCHEMBL3584383	0.82	COMT (0.50)	COMTNPC1RAB9AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.