Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | CASP3 | P42574 | 2/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.60 |
| ▸ | LCK | P06239 | 10/20 | 0.58 |
| ▸ | KDR | P35968 | 10/20 | 0.58 |
| ▸ | HCK | P08631 | 9/20 | 0.58 |
| ▸ | SRC | P12931 | 8/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3585873 | 0.99 | KMT2A (0.60) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL4184434 | 0.93 | NPC1 (0.72) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL4178000 | 0.92 | MEN1 (0.75) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL3596913 | 0.89 | LCK (0.67) | KMT2AMEN1NPC1RAB9ACASP3 | |
| Hydrochloric Acid SCHEMBL3599288 | 0.88 | LCK (0.66) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL3584089 | 0.87 | MEN1 (0.53) | KMT2AMEN1NPC1RAB9ACASP3 | |
| Hydrochloric Acid SCHEMBL4306627 | 0.86 | MEN1 (0.53) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL4182112 | 0.85 | LCK (0.56) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL4170265 | 0.84 | MEN1 (0.58) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL3588495 | 0.82 | LCK (0.83) | KMT2AMEN1NPC1RAB9ALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
| US-20100029636-A1 | Lck inhibitors | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | LCK, ZAP70, FYN | KMT2A 1321/4885MEN1 4411/4885NPC1 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.