Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 10/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007364 | 0.89 | OPRL1 (0.65) | OPRL1OPRM1OPRK1OPRD1CHRNA7 | |
| SCHEMBL7534947 | 0.77 | CHRNA7 (0.71) | OPRL1OPRM1OPRK1OPRD1CHRNA7 | |
| SCHEMBL3591840 | 0.77 | CHRNA7 (0.71) | OPRL1OPRM1OPRK1OPRD1CHRNA7 | |
| SCHEMBL3591843 | 0.77 | CHRNA7 (0.71) | OPRL1OPRM1OPRK1OPRD1CHRNA7 | |
| SCHEMBL3583844 | 0.76 | CHRM1 (0.55) | OPRL1OPRM1OPRK1OPRD1CHRM3 | |
| SCHEMBL3588497 | 0.76 | OPRL1 (0.61) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL3590742 | 0.74 | OPRL1 (0.45) | OPRL1OPRM1OPRK1OPRD1CHRNA7 | |
| Hydrochloric Acid SCHEMBL7883807 | 0.74 | OPRL1 (0.84) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL3592440 | 0.70 | IDO1 (0.41) | OPRL1OPRM1OPRK1 | |
| SCHEMBL7878455 | 0.70 | CHRNA7 (0.65) | OPRL1OPRM1OPRK1OPRD1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877779-B2 | Benzimidazole compound and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2014-11-04 | — | — | US | disclosed |
| US-20100120841-A1 | BENZIMIDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-05-13 | — | — | US | disclosed |
| EP-2128154-A1 | BENZIMIDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120841-A1 | BENZIMIDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | ORMDL3, OXA1L, OGFRL1 | OPRL1 11/4885OPRM1 55/4885OPRK1 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.