⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205893 | 0.84 | — | — | |
| SCHEMBL30612349 | 0.76 | CXCR4 (0.33) | — | |
| SCHEMBL8780336 | 0.73 | — | — | |
| Pyridine SCHEMBL28159856 | 0.69 | PLD1 (0.36) | — | |
| SCHEMBL4922322 | 0.69 | — | — | |
| SCHEMBL27610891 | 0.69 | — | — | |
| SCHEMBL29040960 | 0.69 | CA12 (0.30) | — | |
| SCHEMBL3597162 | 0.68 | — | — | |
| SCHEMBL28266642 | 0.68 | KDM4E (0.32) | — | |
| SCHEMBL4219083 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079050-B1 | 4-AROYLIMIDAZOLIDIN-2-ONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-04-08 | — | — | EP | claimed |
| EP-0079050-A1 | 4-Aroylimidazolidin-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-05-18 | — | — | EP | claimed |
| CN-108137512-A | Cyclic n nitroso compound-amide compound as herbicide | 杜邦公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-101341119-B | Higher fatty acid triester and amide derivative having diethylenetriamine-type metal chelate structure | FUJI PHOTO FILM CO LTD | 2012-06-27 | — | — | CN | disclosed |
| US-20100190768-A1 | NOVEL FUSED PYROLE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| CN-101646655-A | Imidazolidine carboxamide derivatives as lipase and phospholipase inhibitors | SANOFI AVENTIS FR | 2010-02-10 | — | — | CN | disclosed |
| CN-101341119-A | Higher fatty acid triester and amide derivative having diethylenetriamine-type metal chelate structure | FUJIFILM CORP (JP) | 2009-01-07 | — | — | CN | disclosed |
| EP-1930320-A1 | NOVEL FUSED PYRROLE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
| CN-1119345-C | Benzo (5,6) cycloheptapyridine compounds useful as farnesyl protein transferase inhibitors | SCHERING CORP (US) | 2003-08-27 | — | — | CN | disclosed |
| CN-1267302-A | Benzo (5.6) cycloheptopyridine compounds useful as farnesyl protein transferase inhibitors | SCHERING CORP (US) | 2000-09-20 | — | — | CN | disclosed |
| US-4937240-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-06-26 | — | — | US | disclosed |
| EP-0328924-A2 | Thienotriazolodiazepine compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0079050-B1 | 4-AROYLIMIDAZOLIDIN-2-ONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-04-08 | — | — | EP | disclosed |
| US-4410540-A | Cardiotonic 4-aroylimidazolidin-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-10-18 | — | — | US | disclosed |
| EP-0079050-A1 | 4-Aroylimidazolidin-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-05-18 | — | — | EP | disclosed |