Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31042538 | 0.88 | CHRM4 (0.49) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4228148 | 0.83 | AR (0.51) | AR | |
| SCHEMBL6070324 | 0.82 | AR (0.48) | ARMAPT | |
| SCHEMBL3611354 | 0.80 | AR (0.61) | AR | |
| SCHEMBL3598414 | 0.79 | AR (0.57) | AR | |
| SCHEMBL3607872 | 0.79 | AR (0.59) | AR | |
| SCHEMBL31042555 | 0.79 | CHRM4 (0.44) | MAPT | |
| SCHEMBL3605320 | 0.78 | AR (0.58) | AR | |
| SCHEMBL3609225 | 0.77 | AR (0.61) | AR | |
| SCHEMBL4235326 | 0.77 | AR (0.48) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553074-B1 | FUSED BENZENE DERIVATIVE AND USE | TAKEDA PHARMACEUTICAL (JP) | 2014-06-18 | — | — | EP | disclosed |
| US-7649001-B2 | Fused benzene derivative and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-19 | — | — | US | disclosed |