⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691355 | 0.78 | — | — | |
| SCHEMBL9572355 | 0.75 | — | — | |
| SCHEMBL11831715 | 0.74 | — | — | |
| SCHEMBL1943420 | 0.73 | — | — | |
| SCHEMBL6847839 | 0.73 | — | — | |
| SCHEMBL14118196 | 0.73 | — | — | |
| SCHEMBL4189242 | 0.70 | — | — | |
| SCHEMBL27547774 | 0.70 | — | — | |
| SCHEMBL28144542 | 0.69 | — | — | |
| SCHEMBL577189 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373774-A | Preparation method of 2-propyne-1-yl-1H-imidazole-1-carboxylic acid ester | 景德镇富祥生命科技有限公司 | 2024-07-23 | — | — | CN | claimed |
| CN-118373774-A | Preparation method of 2-propyne-1-yl-1H-imidazole-1-carboxylic acid ester | 景德镇富祥生命科技有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-118373774-A | Preparation method of 2-propyne-1-yl-1H-imidazole-1-carboxylic acid ester | 景德镇富祥生命科技有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-115052879-B | Compounds consisting of C20 modified salinomycin derivatives, process for obtaining them, compositions comprising them, use of the compounds and process for obtaining intermediates | 菲莱克洛有限责任公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117624018-A | Parami Wei Naxian guanidine derivative and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2024-03-01 | — | — | CN | disclosed |
| CN-115052879-A | Compound consisting of C20 modified salinomycin derivatives, method for obtaining same, composition comprising same, use of said compound and method for obtaining intermediate product | 菲莱克洛有限责任公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-107106708-B | MRI imaging of amyloid plaques using liposomes | 德克萨斯州儿童医院 | 2021-06-18 | — | — | CN | disclosed |
| CN-105307685-B | Pyrrolobenzodiazepines Zhuo and its conjugate | 麦迪穆有限责任公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-105307685-A | Pyrrolobenzodiazepines and conjugates thereof | SPIROGEN SARL | 2016-02-03 | — | — | CN | disclosed |
| CN-101535237-B | Pentafluorophenyloxy compound, nonaqueous electrolytic solution and lithium secondary battery using the same | UBE INDUSTRIES | 2013-04-24 | — | — | CN | disclosed |
| US-8071637-B2 | Dithiolopyrrolones compounds and their therapeutic applications | WELICHEM BIOTECH INC. (CA) | 2011-12-06 | — | — | US | disclosed |
| US-7794876-B2 | Pentafluorophenyloxy compound, and nonaqueous electrolyte solution and lithium secondary battery using same | UBE INDUSTRIES, LTD. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20100041729-A1 | DITHIOLOPYRROLONES COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | CELESTIAL PHARMACEUTICALS (SHENZHEN) LTD. (CN) | 2010-02-18 | — | — | US | disclosed |
| CN-101535237-A | Pentafluorophenyloxy compound, nonaqueous electrolytic solution and lithium secondary battery using the same | UBE INDUSTRIES | 2009-09-16 | — | — | CN | disclosed |
| EP-2076519-A2 | NOVEL DITHIOLOPYRROLONES AND THEIR THERAPEUTICAL APPLICATIONS | Celestial Pharmaceuticals (Shenzhen) LTD. (CN) | 2009-07-08 | — | — | EP | disclosed |
| US-20080107969-A1 | Pentafluorophenyl Methyl Oxalate; good electrical, cycling and storage properties; reacting pentafluorophenol with ethyl chloroglyoxylate | UBE INDUSTRIES, LTD. (JP) | 2008-05-08 | — | — | US | disclosed |
| WO-2008038175-A2 | DITHIOLOPYRROLONES COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | CELESTIAL PHARMACEUTICALS (SHENZHEN) LTD. (CN) | 2008-04-03 | — | — | WO | disclosed |
| US-4472300-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| US-4237305-A | INTERMEDIATES FOR PREPARING NEW ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-12-02 | — | — | US | disclosed |
| US-4207234-A | 4-Unsubstituted azetidinone derivatives and process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-06-10 | — | — | US | disclosed |