Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 20/20 | 0.91 |
| ▸ | AKT2 | P31751 | 20/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10264783 | 0.95 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL15124038 | 0.87 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL10265242 | 0.87 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL363088 | 0.86 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL359993 | 0.83 | AKT1 (0.78) | AKT1AKT2 | |
| SCHEMBL10264897 | 0.82 | AKT2 (1.00) | AKT1AKT2 | |
| SCHEMBL10268665 | 0.81 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL360763 | 0.81 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL361086 | 0.79 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL15130831 | 0.79 | AKT1 (1.00) | AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593451-A2 | SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AND -PYRIDINES | Bayer Intellectual Property GmbH (DE) | 2013-05-22 | — | — | EP | claimed |
| WO-2012007345-A2 | SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AND -PYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | claimed |