⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2719176 | 0.75 | — | — | |
| SCHEMBL561982 | 0.65 | — | — | |
| SCHEMBL2996874 | 0.63 | — | — | |
| SCHEMBL17831577 | 0.60 | MEN1 (0.34) | — | |
| SCHEMBL2721569 | 0.59 | — | — | |
| SCHEMBL58830 | 0.58 | — | — | |
| SCHEMBL10939367 | 0.57 | — | — | |
| SCHEMBL19981921 | 0.57 | — | — | |
| Alcohol SCHEMBL18092815 | 0.57 | — | — | |
| Hydrochloric Acid SCHEMBL4450181 | 0.56 | TDP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709491-B2 | Substituted quinazolines as antiviral agents, especially against cytomegaloviruses | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-05-04 | — | — | US | disclosed |
| US-20060235032-A1 | Substituted quinazolines as antiviral agents, especially against cytomegaloviruses | AIC246 AG & CO. KG (DE) | 2006-10-19 | — | — | US | disclosed |
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-0759429-B1 | Substituted trifluormethylpyridines useful as intermediates for herbicidal 1-(pyridyl)-pyrazoles | BASF AG (DE) | 2001-10-24 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |
| EP-0759429-A1 | Substituted trifluormethylpyridines useful as intermediates for herbicidal 1-(pyridyl)-pyrazoles | BASF Aktiengesellschaft (DE) | 1997-02-26 | — | — | EP | disclosed |