SCHEMBL3602211

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3616426	0.91	PLK1 (0.46)	PLK1IKBKENEK2FGFR1SRC
	SCHEMBL3258683	0.88	PLK1 (0.50)	PLK1IKBKEGABRPGABRDGABRA1
	SCHEMBL3615059	0.82	PLK1 (0.53)	PLK1NEK2FGFR1SRCPLK4
	SCHEMBL5008887	0.80	PLK1 (0.61)	PLK1IKBKENEK2FGFR1CSF1R
	SCHEMBL3617056	0.79	FGFR1 (0.53)	PLK1NEK2FGFR1SRCPLK4
	SCHEMBL3251789	0.79	PLK1 (0.50)	PLK1IKBKENEK2JAK2JAK3
	SCHEMBL3615700	0.78	PLK1 (0.54)	PLK1IKBKENEK2FGFR1SRC
	SCHEMBL3607621	0.77	PLK1 (0.47)	PLK1IKBKENEK2FGFR1SRC
	SCHEMBL3610351	0.77	PLK1 (0.47)	PLK1IKBKENEK2FGFR1SRC
	SCHEMBL3607331	0.76	PLK1 (0.48)	PLK1NEK2FGFR1SRCPLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.