Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3603119 | 1.00 | SGPL1 (0.76) | SGPL1SMO | |
| SCHEMBL20431356 | 0.89 | SGPL1 (0.63) | SGPL1SMO | |
| SCHEMBL20431354 | 0.88 | SMO (0.79) | SGPL1SMO | |
| SCHEMBL3600788 | 0.86 | SGPL1 (1.00) | SGPL1SMO | |
| SCHEMBL3600783 | 0.86 | SGPL1 (1.00) | SGPL1SMO | |
| SCHEMBL13445145 | 0.85 | SMO (0.79) | SGPL1SMO | |
| SCHEMBL3611158 | 0.84 | SMO (0.71) | SGPL1SMO | |
| SCHEMBL20431242 | 0.84 | SMO (0.71) | SGPL1SMO | |
| SCHEMBL14084447 | 0.83 | SMO (0.75) | SGPL1SMO | |
| SCHEMBL14084446 | 0.83 | SMO (0.75) | SGPL1SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536168-B2 | Benzyl and pyridinyl derivatives as modulators of the hedgehog signaling pathway | NOVARTIS AG (CH) | 2013-09-17 | — | — | US | disclosed |
| CN-101657430-B | Organic compounds and uses thereof | NOVARTIS AG CH | 2013-05-01 | — | — | CN | disclosed |
| US-20100069368-A1 | Organic Compounds and Their Uses | NOVARTIS AG (CH) | 2010-03-18 | — | — | US | disclosed |
| CN-101657430-A | Organic compounds and uses thereof | NOVARTIS AG CH | 2010-02-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069368-A1 | Organic Compounds and Their Uses | SHH, GLI1, VHL | SGPL1 3140/4885SMO 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.