SCHEMBL360445

SCHEMBL360445

C=CCC(C(=O)Cl)C(=O)Cl

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.35
GRIK2 Q13002 2/20 0.35
CYP2C19 P33261 1/20 0.34
CPA1 P15085 1/20 0.34
ABCC4 O15439 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20474539 0.87 GRIK1 (0.41) GRIK1GRIK2CYP2C19CPA1ABCC4
SCHEMBL10941877 0.84 GRIK1 (0.31) GRIK1GRIK2
SCHEMBL29497160 0.78 GRIK1 (0.45) GRIK1GRIK2CYP2C19CPA1ABCC4
SCHEMBL31636 0.77 GRIK1 (0.48) GRIK1GRIK2CYP2C19CPA1ABCC4
Ammonia Solution, Strong SCHEMBL6396419 0.74 GRIK1 (0.46) GRIK1GRIK2CYP2C19CPA1ABCC4
SCHEMBL31299617 0.74 GRIK1 (0.46) GRIK1GRIK2CYP2C19CPA1ABCC4
Lithium SCHEMBL31299623 0.74 GRIK1 (0.46) GRIK1GRIK2CYP2C19CPA1ABCC4
Potassium SCHEMBL31299609 0.74 GRIK1 (0.46) GRIK1GRIK2CYP2C19CPA1ABCC4
SCHEMBL9622027 0.74
SCHEMBL2704693 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118255545-B High-hardness silicon-free artificial stone plate and preparation method thereof 东莞市欧亚轩装饰建材有限公司 2024-09-17 CN claimed
CN-118255545-A High-hardness silicon-free artificial stone plate and preparation method thereof 东莞市欧亚轩装饰建材有限公司 2024-06-28 CN claimed
CN-116836366-B Super soft sponge 东莞市腾崴塑胶制品有限公司 2024-01-30 CN claimed
CN-116836366-A Super soft sponge 东莞市腾崴塑胶制品有限公司 2023-10-03 CN claimed
EP-0018139-B1 PYRIDO (2,3-D) PYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR PREPARING THE PYRIDO (2,3-D) PYRIMIDINE DERIVATIVES AMERICAN HOME PRODUCTS CORPORATION (US) 1983-05-04 EP claimed
EP-0018139-A2 Pyrido (2,3-d) pyrimidine derivatives, pharmaceutical compositions containing them and processes for preparing the pyrido (2,3-d) pyrimidine derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1980-10-29 EP claimed
EP-0010426-A1 Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof ELI LILLY AND COMPANY (US) 1980-04-30 EP claimed
US-12616773-B2 Bioadhesive compositions and methods of making the same THE PENN STATE RESEARCH FOUNDATION (US) 2026-05-05 US disclosed
WO-2025081182-A1 CITRATE-BASED OCULAR IMPLANTS AND POLYMERS THE PENN STATE RESEARCH FOUNDATION (US) 2025-04-17 WO disclosed
US-20240409684-A1 Ion-Crosslinked Polymeric or Oligomeric Compositions THE PENN STATE RESEARCH FOUNDATION 2024-12-12 US disclosed
CN-118255545-B High-hardness silicon-free artificial stone plate and preparation method thereof 东莞市欧亚轩装饰建材有限公司 2024-09-17 CN disclosed
EP-4001342-B1 BIOELASTOMERS AND APPLICATIONS THEREOF PENN STATE RES FOUND (US) 2024-08-21 EP disclosed
CN-118255545-A High-hardness silicon-free artificial stone plate and preparation method thereof 东莞市欧亚轩装饰建材有限公司 2024-06-28 CN disclosed
US-4350817-A 4-Cl, Br or I-3-Carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1982-09-21 US disclosed
US-4347362-A HYPOTENSIVE AMERICAN HOME PRODUCTS CORPORATION (US) 1982-08-31 US disclosed
US-4324893-A 4-Amino-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1982-04-13 US disclosed
EP-0018735-A1 1,8-Naphthyridine derivatives, their preparation, pharmaceutical compositions containing them AMERICAN HOME PRODUCTS CORPORATION (US) 1980-11-12 EP disclosed
WO-1980002287-A1 1,8-NAPHTHYRIDINE DERIVATIVES AMERICAN HOME PROD (US) 1980-10-30 WO disclosed
EP-0010426-A1 Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof ELI LILLY AND COMPANY (US) 1980-04-30 EP disclosed
EP-0010426-A1 Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof ELI LILLY AND COMPANY (US) 1980-04-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616773-B2 Bioadhesive compositions and methods of making the same F12, F13A1, EPCAM GRIK1 1478/4885GRIK2 1431/4885CYP2C19 1898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.