Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.39 |
| ▸ | RPLP1 | P05386 | 6/20 | 0.39 |
| ▸ | RPLP0 | P05388 | 6/20 | 0.39 |
| ▸ | RPS17 | P08708 | 6/20 | 0.39 |
| ▸ | RPSA | P08865 | 6/20 | 0.39 |
| ▸ | RPS2 | P15880 | 6/20 | 0.39 |
| ▸ | RPL35A | P18077 | 6/20 | 0.39 |
| ▸ | RPL7 | P18124 | 6/20 | 0.39 |
| ▸ | RPL17 | P18621 | 6/20 | 0.39 |
| ▸ | RPS4Y1 | P22090 | 6/20 | 0.39 |
| ▸ | RPS3 | P23396 | 6/20 | 0.39 |
| ▸ | RPS12 | P25398 | 6/20 | 0.39 |
| ▸ | RPL13 | P26373 | 6/20 | 0.39 |
| ▸ | RPL10 | P27635 | 6/20 | 0.39 |
| ▸ | RPL12 | P30050 | 6/20 | 0.39 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769714 | 0.84 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL330261 | 0.84 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL4768112 | 0.82 | CYP3A4 (0.45) | — | |
| SCHEMBL330236 | 0.82 | CYP3A4 (0.45) | — | |
| SCHEMBL330631 | 0.79 | TACR1 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL330630 | 0.79 | TACR1 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL330952 | 0.79 | TACR1 (0.35) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL330350 | 0.79 | TACR1 (0.35) | SLC6A2SLC6A4SLC6A3CYP2D6TACR1 | |
| SCHEMBL330351 | 0.79 | TACR1 (0.35) | SLC6A2SLC6A4SLC6A3CYP2D6TACR1 | |
| SCHEMBL330622 | 0.78 | TACR1 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2407451-A1 | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors | Otsuka Pharmaceutical Co., Ltd. (JP) | 2012-01-18 | — | — | EP | disclosed |