SCHEMBL3606556

SCHEMBL3606556

CC(COCc1ccccc1)Oc1cc(Br)cc(C#N)c1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.40
TACR1 P25103 7/20 0.38
CA1 P00915 4/20 0.36
CA2 P00918 2/20 0.34
CA7 P43166 2/20 0.34
CA9 Q16790 2/20 0.34
KMT2A Q03164 1/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3598854 0.86 MAOB (0.39) MAOBTACR1CA1CA2CA7
SCHEMBL27700942 0.83 MAOB (0.43) MAOBKMT2A
SCHEMBL3588948 0.81 MEN1 (0.48) MAOBTACR1CA1KMT2A
SCHEMBL3601252 0.80 GCK (0.31)
SCHEMBL3596082 0.79 GCK (0.36)
SCHEMBL3595253 0.78 GCK (0.45)
SCHEMBL9986858 0.78 GCK (0.45)
SCHEMBL2655610 0.78 MAOB (0.52) MAOBKMT2A
SCHEMBL22489859 0.77 MAOB (0.63) MAOBKMT2A
SCHEMBL20259514 0.76 MAOB (0.46) MAOBTACR1CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101039901-B Process for making phenoxy benzamide compounds ASTRAZENECA AB 2011-03-09 CN disclosed
US-7700640-B2 Process for making phenoxy benzamide compounds ASTRAZENECA AB (SE) 2010-04-20 US disclosed
US-20080200694-A1 Process for Making Phenoxy Benzamide Compounds ASTRAZENECA AB (SE) 2008-08-21 US disclosed
CN-101039901-A Process for making phenoxy benzamide compounds ASTRAZENECA AB (SE) 2007-09-19 CN disclosed
EP-1802570-A1 PROCESS FOR MAKING PHENOXY BENZAMIDE COMPOUNDS AstraZeneca AB (SE) 2007-07-04 EP disclosed
WO-2006040527-A1 PROCESS FOR MAKING PHENOXY BENZAMIDE COMPOUNDS ASTRAZENECA AB (SE) 2006-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200694-A1 Process for Making Phenoxy Benzamide Compounds PAH, MAOB, TYR MAOB 2/4885TACR1 2406/4885CA1 2044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.