Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670432 | 0.98 | KCNH2 (0.42) | KCNH2TLR8LIPGMAPTHTT | |
| SCHEMBL409777 | 0.98 | KCNH2 (0.42) | KCNH2TLR8LIPGMAPTHTT | |
| SCHEMBL9145259 | 0.98 | KCNH2 (0.42) | KCNH2TLR8LIPGMAPTHTT | |
| SCHEMBL3281783 | 0.98 | KCNH2 (0.42) | KCNH2TLR8LIPGMAPTHTT | |
| SCHEMBL2460770 | 0.98 | KCNH2 (0.42) | KCNH2TLR8LIPGMAPTHTT | |
| SCHEMBL3282347 | 0.98 | KCNH2 (0.42) | KCNH2TLR8LIPGMAPTHTT | |
| SCHEMBL3670490 | 0.98 | KCNH2 (0.42) | KCNH2TLR8LIPGMAPTHTT | |
| SCHEMBL3670506 | 0.98 | KCNH2 (0.42) | KCNH2TLR8LIPGMAPTHTT | |
| SCHEMBL3671647 | 0.98 | KCNH2 (0.42) | KCNH2TLR8LIPGMAPTHTT | |
| SCHEMBL3284970 | 0.98 | KCNH2 (0.42) | KCNH2TLR8LIPGMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109704913-A | A kind of spiro fluorene compound and its application | 瑞声科技（南京）有限公司 | 2019-05-03 | — | — | CN | claimed |
| EP-2895472-B1 | Tricyclic alkene derivatives as HIV attachment inhibitors | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2016-11-23 | — | — | EP | claimed |
| EP-2751119-B1 | FUSED BICYCLIC DIAMINE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2016-11-23 | — | — | EP | claimed |
| EP-2895475-B1 | TRICYCLIC AMIDINE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2016-11-09 | — | — | EP | claimed |
| EP-2751118-B1 | SPIRO BICYCLIC DIAMINE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-10-12 | — | — | EP | claimed |
| US-8900725-B2 | Dendrimer and organic light-emitting device using the same | SAMSUNG DISPLAY CO., LTD. | 2014-12-02 | — | — | US | claimed |
| US-8865322-B2 | Dendrimer and organic light-emitting device using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-10-21 | — | — | US | claimed |
| EP-2407501-B1 | Dendrimer and organic light-emitting device using the same | SAMSUNG DISPLAY CO LTD (KR) | 2013-09-11 | — | — | EP | claimed |
| EP-2407502-B1 | Dendrimer and organic light-emitting device using the same | SAMSUNG DISPLAY CO LTD (KR) | 2013-06-19 | — | — | EP | claimed |
| US-8455866-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2013-06-04 | — | — | US | claimed |
| US-20050080087-A1 | Pyrazole derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2005-04-14 | — | — | US | claimed |
| EP-1265976-B1 | LUBRICANT COMPOSITIONS COMPRISING A DISPERSANT, A TRINUCLEAR MOLYBDENUM COMPOUND AND A DIFFERENT ANTIOXIDANT | EXXONMOBIL RES & ENG CO (US) | 2004-11-17 | — | — | EP | claimed |
| US-20040121920-A1 | For use in diesel engines | EXXONMOBIL RESEARCH & ENGINEERING CO. | 2004-06-24 | — | — | US | claimed |
| JP-2003523456-A | — | — | 2003-08-05 | — | — | JP | claimed |
| EP-1280873-A1 | ANTIOXIDANT ADDITIVE COMPOSITION FOR LUBRICATING OILS | ExxonMobil Research and Engineering Company (US) | 2003-02-05 | — | — | EP | claimed |
| EP-1265976-A1 | LUBRICANT COMPOSITIONS COMPRISING A DISPERSANT, A TRINUCLEAR MOLYBDENUM COMPOUND AND A DIFFERENT ANTIOXIDANT | ExxonMobil Research and Engineering Company (US) | 2002-12-18 | — | — | EP | claimed |
| EP-1149819-A1 | An improved process for acylation of naphthyl ethers | Council of Scientific and Industrial Research (IN) | 2001-10-31 | — | — | EP | claimed |
| WO-2001060959-A1 | ANTIOXIDANT ADDITIVE COMPOSITION FOR LUBRICATING OILS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2001-08-23 | — | — | WO | claimed |
| WO-2001060957-A1 | LUBRICANT COMPOSITION COMPRISING A DISPERSANT, A TRINUCLEAR MOLYBDENUM COMPOUND AND A DIFFERENT OTHER ANTIOXIDANT | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2001-08-23 | — | — | WO | claimed |
| WO-2001059041-A1 | LUBRICATING OIL COMPOSITIONS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2001-08-16 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080087-A1 | Pyrazole derivatives as cannabinoid receptor modulators | CNR1, CNR2, NPY1R | KCNH2 1695/4885TLR8 3070/4885LIPG 2016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.