⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1676981 | 1.00 | — | — | |
| SCHEMBL5056747 | 1.00 | — | — | |
| SCHEMBL1394505 | 1.00 | — | — | |
| SCHEMBL6372815 | 1.00 | — | — | |
| SCHEMBL4044077 | 1.00 | — | — | |
| SCHEMBL3213745 | 0.76 | — | — | |
| SCHEMBL9145456 | 0.74 | — | — | |
| SCHEMBL5798207 | 0.72 | — | — | |
| SCHEMBL3667167 | 0.72 | — | — | |
| SCHEMBL270306 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3921319-B1 | IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEIGENE LTD (KY) | 2024-03-06 | — | — | EP | claimed |
| US-20230167117-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEONE MEDICINES I GMBH (CH) | 2023-06-01 | — | — | US | claimed |
| CN-113423708-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-103012336-A | Water-soluble amino-acid ester derivative of andrographolide and dehydroandrographolide | BEIJING MEIBEITA PHARMACEUTICAL RES CO LTD | 2013-04-03 | — | — | CN | claimed |
| CN-102049048-A | Method of treatment or prophylaxis | SPINIFEX PHARM PTY LTD | 2011-05-11 | — | — | CN | claimed |
| CN-101812105-A | Cytarabine 5'-O-amino-acid ester, salts thereof and preparation method thereof | UNIV SHENYANG PHARMACEUTICAL | 2010-08-25 | — | — | CN | claimed |
| US-20100056522-A1 | INTRAOCULAR PRESSURE-LOWERING AGENT COMPRISING COMPOUND HAVING HISTONE DEACETYLASE INHIBITOR EFFECT AS ACTIVE INGREDIENT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2010-03-04 | — | — | US | claimed |
| CN-101443001-A | Methods of treating or preventing inflammatory pain | UNIV QUEENSLAND (AU) | 2009-05-27 | — | — | CN | claimed |
| CN-101376651-A | Water-soluble amino acid ester derivatives of andrographolide and dehydroandrographolide | BEIJING MEIBEITA DRUG RES CO L (CN) | 2009-03-04 | — | — | CN | claimed |
| CN-101374551-A | Novel glycolipid adjuvant compositions | PFIZER PROD INC (US) | 2009-02-25 | — | — | CN | claimed |
| CN-1500800-A | Nucleoside analogs as antiviral agents for retroviral reverse transcriptase and DNA polymerase inhibitors | ά | 2004-06-02 | — | — | CN | claimed |
| CN-1113874-C | Benzocycloalkylazolethione derivatives | SYNTEX INC (US) | 2003-07-09 | — | — | CN | claimed |
| US-20020065230-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2002-05-30 | — | — | US | claimed |
| EP-0683792-B1 | LHRH ANTAGONISTS HAVING MODIFIED AMINOACYL RESIDUES AT POSTIONS 5 AND 6 | ABBOTT LAB (US) | 2001-09-26 | — | — | EP | claimed |
| CN-1275983-A | Nucleoside analogues, these compounds as antiviral agents comprising inhibitors of the reverse transcriptase and DNA polymerase of retroviruses of Hepatitis B Virus (HBV) | MEDIVIR AB (SE) | 2000-12-06 | — | — | CN | claimed |
| CN-1151735-A | Benzocycloalkylazolethione derivatives | SYNTEX INC (US) | 1997-06-11 | — | — | CN | claimed |
| JP-H08505611-A | — | — | 1996-06-18 | — | — | JP | claimed |
| CN-1104209-A | 2,4-diamino-3-hydroxycarboxylic acid derivatives | SANDOZ LTD (CH) | 1995-06-28 | — | — | CN | claimed |
| EP-0296122-B1 | CYCLOSPORINS AND THEIR USE AS PHARMACEUTICALS | SANDOZ AG (CH) | 1993-09-29 | — | — | EP | claimed |
| EP-0296122-A2 | Cyclosporins and their use as pharmaceuticals | SANDOZ AG (CH) | 1988-12-21 | — | — | EP | claimed |