Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16390593 | 0.87 | BACE1 (0.57) | BACE1 | |
| SCHEMBL1910411 | 0.85 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL360663 | 0.85 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL1173499 | 0.85 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL7686334 | 0.84 | BACE1 (0.84) | BACE1APP | |
| SCHEMBL361728 | 0.83 | BACE1 (1.00) | BACE1 | |
| SCHEMBL1173053 | 0.83 | BACE1 (0.79) | BACE1APP | |
| SCHEMBL361102 | 0.83 | BACE1 (1.00) | BACE1 | |
| SCHEMBL362158 | 0.83 | BACE1 (1.00) | BACE1 | |
| SCHEMBL360873 | 0.83 | BACE1 (1.00) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009943-A1 | OXAZINE DERIVATIVES AND THEIR USE AS BACE INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | claimed |
| WO-2011009943-A1 | OXAZINE DERIVATIVES AND THEIR USE AS BACE INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | disclosed |